| UniProt/SwissProt ID: | SPF45_HUMAN |
| Description: | RNA binding motif protein 17 [Source:HGNC Symbol;Acc:16944] |
| Location: | chr10 p15.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S227 | SPTGPsNSFLA | PhosphoSitePlus; HPRD | |
| S85 | KDPVPsGFSAG | PhosphoSitePlus | |
| S155 | RPDPDsDEDED | PhosphoSitePlus; HPRD; phosphoELM | |
| S28 | FKLLQsQLQVK | PhosphoSitePlus | |
| Y194 | PRDFPyEEDSR | PhosphoSitePlus | |
| S180 | IAPPTsLVEKD | PhosphoSitePlus | |
| T179 | AIAPPtSLVEK | PhosphoSitePlus; HPRD | |
| S169 | ERRKRsMGGAA | PhosphoSitePlus; HPRD; phosphoELM | |
| T71 | RQIVDtPPHVA | PhosphoSitePlus; HPRD | |
| Y161 | DEDEDyERERR | PhosphoSitePlus | |
| S293 | SKKSDsNPLTE | PhosphoSitePlus; HPRD | |
| S204 | RPRSQsSKAAI | PhosphoSitePlus; HPRD; phosphoELM | |
| Y214 | IPPPVyEEQDR | PhosphoSitePlus | |
| S229 | TGPSNsFLANM | PhosphoSitePlus; HPRD | |
| S222 | QDRPRsPTGPS | PhosphoSitePlus; HPRD; phosphoELM | |
| T224 | RPRSPtGPSNS | PhosphoSitePlus; HPRD; phosphoELM | |
| Dephosphorylation site |
| SPF45_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000369218 | G247V | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000388638 | G247V | BIOMART | Breast Cancer | 21930507, 21930502 |
| Differential expressed protein |
| SPF45_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SPF45_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CSK22_HUMAN | SPF45_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| WEE1_HUMAN | SPF45_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| AKT1_HUMAN | SPF45_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ST17A_HUMAN | SPF45_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| DYRK3_HUMAN | SPF45_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CSK21_HUMAN | SPF45_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| SPF45_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0005681 | spliceosomal complex | IEA | cellular_component |
| GO:0000166 | nucleotide binding | IEA | molecular_function |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0008380 | RNA splicing | IEA | biological_process |
| GO:0006397 | mRNA processing | IEA | biological_process |