| UniProt/SwissProt ID: | SKAP1_HUMAN |
| Description: | src kinase associated phosphoprotein 1 [Source:HGNC Symbol;Acc:15605] |
| Location: | chr17 q21.32 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y298 | VDYASyYQGLW | PhosphoSitePlus | |
| Y143 | GLFYYyANEKS | PH | PhosphoSitePlus |
| T262 | GIKEPtEEKEE | PhosphoSitePlus | |
| Y295 | RKGVDyASYYQ | FYN | RegPhos |
| Y142 | RGLFYyYANEK | PH | PhosphoSitePlus |
| Y232 | EKEETyDDIDG | Fyn | phosphoELM; RegPhos |
| Y295 | RKGVDyASYYQ | PhosphoSitePlus | |
| Y141 | SRGLFyYYANE | PH | PhosphoSitePlus |
| Y299 | DYASYyQGLWD | PhosphoSitePlus | |
| Y219 | SLTIPyEEDEE | PhosphoSitePlus; RegPhos | |
| Y271 | EEEDIyEVLPD | PhosphoSitePlus; phosphoELM; RegPhos | |
| Y219 | SLTIPyEEDEE | Fyn | phosphoELM; RegPhos |
| Y142 | RGLFYyYANEK | phosphoELM; RegPhos | |
| Y271 | EEEDIyEVLPD | FYN | RegPhos |
| Y232 | EKEETyDDIDG | PhosphoSitePlus; RegPhos | |
| Y90 | PFLSDyQDEGM | PhosphoSitePlus | |
| Dephosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y232 | EEEKEETyDDIDGFD | PTPRC | HPRD |
| Mutation site |
| SKAP1_HUMAN do not have mutation site. |
| Differential expressed protein |
| SKAP1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| SKAP1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FYN_HUMAN | SKAP1_HUMAN | kinase -> substrate | RegPhos; NetPath; Robert H Newman (2013) |
| MK14_HUMAN | SKAP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| ZAGL2_HUMAN | SKAP1_HUMAN | kinase -> substrate | RegPhos |
| KC1E_HUMAN | SKAP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK1_HUMAN | SKAP1_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| PTPRC_HUMAN | SKAP1_HUMAN | phosphatase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| SKAP1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005543 | phospholipid binding | IEA | molecular_function |
| GO:0005886 | plasma membrane | IDA | cellular_component |
| GO:0032403 | protein complex binding | IEA | molecular_function |
| GO:0050852 | T cell receptor signaling pathway | IMP | biological_process |
| GO:0003823 | antigen binding | IPI | molecular_function |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005070 | SH3/SH2 adaptor activity | IC | molecular_function |
| GO:0042169 | SH2 domain binding | IEA | molecular_function |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0045944 | positive regulation of transcription from RNA poly | IMP | biological_process |
| GO:0019901 | protein kinase binding | IPI | molecular_function |
| GO:0045893 | positive regulation of transcription, DNA-dependen | IMP | biological_process |
| GO:0005737 | cytoplasm | IDA | cellular_component |