Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SIT1_HUMAN
Description:signaling threshold regulating transmembrane adaptor 1 [Source:HGNC Symbol;Acc:17710]
Location:chr9 p13.3
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y169PEPELyASVCAPhosphoSitePlus; HPRD; phosphoELM
Y188FPDQAyANSQPPhosphoSitePlus; HPRD; phosphoELM
T128EVMCYtSLQLRPhosphoSitePlus
T98LHYLQtGRLSQPhosphoSitePlus; HPRD; phosphoELM
S129VMCYTsLQLRPPhosphoSitePlus
S162PKSQAsGPEPEPhosphoSitePlus
S80PGQGRsGESVEPhosphoSitePlus; HPRD; phosphoELM
Y127EEVMCyTSLQLPhosphoSitePlus; HPRD; phosphoELM
S191QAYANsQPAASPhosphoSitePlus
Y90EEVPLyGNLHYPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S73RGRSRsHPGQGHlyIIIPhosphoSitePlus
S182RRARAsFPDQAPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y148GTPVKySEVVLPhosphoSitePlus; HPRD; phosphoELM; SysPTM
Y95YGNLHyLQTGRPhosphoSitePlus; HPRD; phosphoELM
S171PELYAsVCAQTPhosphoSitePlus
S83GRSGEsVEEVPPhosphoSitePlus; HPRD; phosphoELM
T144IPGPGtPVKYSPhosphoSitePlus; HPRD; phosphoELM
S102QTGRLsQDPEPPhosphoSitePlus; HPRD; phosphoELM
S149TPVKYsEVVLDPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
SIT1_HUMAN do not have dephosphorylation site.

Mutation site
SIT1_HUMAN do not have mutation site.

Differential expressed protein
SIT1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SIT1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
LCK_HUMANSIT1_HUMANkinase -> substrateNetPath
FYN_HUMANSIT1_HUMANkinase -> substrateNetPath

Function Annotation
KEGG Pathway
SIT1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005737cytoplasmIDAcellular_component
GO:0007165signal transductionTASbiological_process
GO:0005730nucleolusIDAcellular_component
GO:0005887integral to plasma membraneTAScellular_component
GO:0019900kinase bindingIPImolecular_function
GO:0050863regulation of T cell activationIDAbiological_process
GO:0042169SH2 domain bindingTASmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005886plasma membraneIDAcellular_component


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