Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SEM4D_HUMAN
Description:sema domain, immunoglobulin domain (Ig), transmembrane domain (TM) and short cytoplasmic domain, (semaphorin) 4D [Source:HGNC Symbol;Acc:10732]
Location:chr9 q22.2
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S788CDREQsLKETLPhosphoSitePlus
T817DTGYEtEQDTIPhosphoSitePlus
S769CLKFRsALLIGPhosphoSitePlus
S857LKFADsDADGDPhosphoSitePlus
Y815ALDTGyETEQDPhosphoSitePlus
S195RNSSHsPLRTEHPRD; SysPTM
T390NLPDKtLQFVKSemaPhosphoSitePlus
S833TDREDsQRIDDPhosphoSitePlus
Y358R.YNGPVPKPR.PSysPTM 2.0

Dephosphorylation site
SEM4D_HUMAN do not have dephosphorylation site.

Mutation site
SEM4D_HUMAN do not have mutation site.

Differential expressed protein
SEM4D_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SEM4D_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SEM4D_HUMANPLXB1_HUMANligand -> receptorHPMR
SEM4D_HUMANPLXB2_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04360Axon guidance

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0071526semaphorin-plexin signaling pathwayIMPbiological_process
GO:0030335positive regulation of cell migrationISSbiological_process
GO:0048672positive regulation of collateral sproutingIMPbiological_process
GO:0001934positive regulation of protein phosphorylationIDAbiological_process
GO:0031344regulation of cell projection organizationIMPbiological_process
GO:0005615extracellular spaceISScellular_component
GO:0030335positive regulation of cell migrationIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIMPbiological_process
GO:0050731positive regulation of peptidyl-tyrosine phosphoryIEAbiological_process
GO:1900220semaphorin-plexin signaling pathway involved in boIEAbiological_process
GO:0050732negative regulation of peptidyl-tyrosine phosphoryISSbiological_process
GO:0010693negative regulation of alkaline phosphatase activiIEAbiological_process
GO:0004888transmembrane signaling receptor activityIMPmolecular_function
GO:0043931ossification involved in bone maturationIEAbiological_process
GO:0008360regulation of cell shapeIMPbiological_process
GO:0005102receptor bindingIEAmolecular_function
GO:0016020membraneIEAcellular_component
GO:0010693negative regulation of alkaline phosphatase activiIMPbiological_process
GO:0005102receptor bindingIDAmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0005615extracellular spaceIEAcellular_component
GO:0007275multicellular organismal developmentIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0030215semaphorin receptor bindingISSmolecular_function
GO:0030215semaphorin receptor bindingIEAmolecular_function
GO:0050772positive regulation of axonogenesisIEAbiological_process
GO:0032321positive regulation of Rho GTPase activityIEAbiological_process
GO:0004872receptor activityIDAmolecular_function
GO:0043931ossification involved in bone maturationIMPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0045668negative regulation of osteoblast differentiationIEAbiological_process
GO:0043066negative regulation of apoptotic processTASbiological_process
GO:0070486leukocyte aggregationIMPbiological_process
GO:1900220semaphorin-plexin signaling pathway involved in boISSbiological_process
GO:0006955immune responseTASbiological_process
GO:0007411axon guidanceTASbiological_process
GO:0014068positive regulation of phosphatidylinositol 3-kinaIMPbiological_process
GO:0045668negative regulation of osteoblast differentiationISSbiological_process
GO:0050731positive regulation of peptidyl-tyrosine phosphoryISSbiological_process
GO:0050732negative regulation of peptidyl-tyrosine phosphoryIEAbiological_process
GO:0048814regulation of dendrite morphogenesisIMPbiological_process
GO:0032321positive regulation of Rho GTPase activityISSbiological_process
GO:0005887integral to plasma membraneIDAcellular_component
GO:0007155cell adhesionTASbiological_process