Phosphorylation

Protein information

UniProt/SwissProt ID:	PLXB2_HUMAN
Description:	plexin B2 [Source:HGNC Symbol;Acc:9104]
Location:	chr22 q13.33
Node attribute:	receptor

Position	PhosphoPeptide	Catalytic kinase	Source
Y1748	KEISTyKKMVE	Plexin_cytopl	PhosphoSitePlus
Y1621	AITEIyLTRLL	Plexin_cytopl; RasGAP	PhosphoSitePlus
Y1422	AGEPLyKLFKA	Plexin_cytopl; RasGAP	PhosphoSitePlus
Y1412	ICLYQyLKDSA	Plexin_cytopl; RasGAP	PhosphoSitePlus
Y1410	MSICLyQYLKD	Plexin_cytopl; RasGAP	PhosphoSitePlus
S1570	QQPEDsQQDLP	Plexin_cytopl; RasGAP	PhosphoSitePlus
T1614	KEKERtKAITE	Plexin_cytopl; RasGAP	PhosphoSitePlus
S1224	CYWRKsQQAER	RAMP	PhosphoSitePlus
S1627	LTRLLsVKGTL	Plexin_cytopl; RasGAP	PhosphoSitePlus
Y1741	SNKLLyAKEIS	Plexin_cytopl	PhosphoSitePlus
Y1499	IIDQVyRGQPC	Plexin_cytopl; RasGAP	PhosphoSitePlus
Y1349	ARAKVyFASLL	Plexin_cytopl	PhosphoSitePlus
S1325	SNLLNsKSFLI	Plexin_cytopl	PhosphoSitePlus
T1124	LNKAMtLQEAE		PhosphoSitePlus; HPRD
Y419	RILKVyLTPDG	Sema	PhosphoSitePlus
S1327	LLNSKsFLINF	Plexin_cytopl	PhosphoSitePlus
Y1231	QAEREyEKIKS		PhosphoSitePlus
S452	SGDLGsLYAMT		PhosphoSitePlus; HPRD
S1320	ALYQFsNLLNS	Plexin_cytopl	PhosphoSitePlus
T1623	TEIYLtRLLSV	Plexin_cytopl; RasGAP	PhosphoSitePlus

PLXB2_HUMAN do not have dephosphorylation site.

Ensembl ID	Variation	Source	Cancer name	Pubmed
ENSP00000352288	R659P	BIOMART	Neoplasms by Histologic Type	21930507, 21930502

PLXB2_HUMAN is not differential expressed protein.

PLXB2_HUMAN do not have hyperphosphorylation site.

Source	Target	Relationship	Resource
SEM4D_HUMAN	PLXB2_HUMAN	ligand -> receptor	HPMR

KEGG Pathway

KEGG ID	Pathway
hsa04360	Axon guidance

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0016020	membrane	IEA	cellular_component
GO:0007275	multicellular organismal development	IEA	biological_process
GO:0071526	semaphorin-plexin signaling pathway	IEA	biological_process
GO:0001932	regulation of protein phosphorylation	IEA	biological_process
GO:0071526	semaphorin-plexin signaling pathway	ISS	biological_process
GO:0008360	regulation of cell shape	IEA	biological_process
GO:0005515	protein binding	IPI	molecular_function
GO:0005622	intracellular	IEA	cellular_component
GO:0050772	positive regulation of axonogenesis	IEA	biological_process
GO:0005887	integral to plasma membrane	IEA	cellular_component
GO:0007405	neuroblast proliferation	IEA	biological_process
GO:0007165	signal transduction	IEA	biological_process
GO:0001843	neural tube closure	IEA	biological_process
GO:0032319	regulation of Rho GTPase activity	IEA	biological_process
GO:0007420	brain development	IEA	biological_process
GO:0005096	GTPase activator activity	IEA	molecular_function
GO:0005515	protein binding	IEA	molecular_function
GO:0017154	semaphorin receptor activity	IEA	molecular_function
GO:0004872	receptor activity	IEA	molecular_function
GO:2001222	regulation of neuron migration	IEA	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network