Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SDC2_HUMAN
Description:syndecan 2 [Source:HGNC Symbol;Acc:10659]
Location:chr8 q22.1
Node attribute:receptor; substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y200PTKEFHPRD
S41SIEEAsGVYPISyndecanPhosphoSitePlus
S188ERKPSsAAYQKPKC_groupphosphoELM; RegPhos
S187GERKPsSAAYQGlycophorin_A; Herpes_gE;PhosphoSitePlus
T196YQKAPtKEFYAHerpes_gE; Syndecan; ProtPhosphoSitePlus
S188ERKPSsAAYQKPKCgRegPhos
Y191PSSAAyQKAPTGlycophorin_A; Herpes_gE;PhosphoSitePlus
S187GERKPsSAAYQPKCaRegPhos
S187GERKPsSAAYQPKCbRegPhos
S187GERKPsSAAYQPKCgRegPhos
Y200PTKEFyA____Herpes_gEPhosphoSitePlus
S187GERKPsSAAYQPKC_groupphosphoELM; RegPhos
S188ERKPSsAAYQKPKCaRegPhos
S188ERKPSsAAYQKPKCbRegPhos
S187GERKPsSAAYQPRKCGHPRD
S187GERKPsSAAYQPRKCBHPRD
Y191PSSAAyQKAPTHPRD
Y179KDEGSyDLGERGlycophorin_A; Herpes_gE;PhosphoSitePlus
S188ERKPSsAAYQKPRKCAHPRD
S188ERKPSsAAYQKPRKCBHPRD
S188ERKPSsAAYQKPRKCGHPRD
S187GERKPsSAAYQPRKCAHPRD
S188ERKPSsAAYQKGlycophorin_A; Herpes_gE;PhosphoSitePlus

Dephosphorylation site
SDC2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000307046V43GCOSMICOvarian Cancer21720365
ENSP00000307046V43GTCGAOvarian Cancer21720365, 18772890
ENSP00000307046D108NBIOMARTBreast Cancer21930507, 21930502
ENSP00000441453V43GTCGAOvarian Cancer21720365, 18772890
ENSP00000307046E125KTCGAOvarian Cancer21720365, 18772890
ENSP00000441453E125KTCGAOvarian Cancer21720365, 18772890
ENSP00000307046E125KCOSMICOvarian Cancer21720365

Differential expressed protein
SDC2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SDC2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FGF2_HUMANSDC2_HUMANligand -> receptorHPMR
KPCA_HUMANSDC2_HUMANkinase -> substrateHPRD
KPCB_HUMANSDC2_HUMANkinase -> substrateHPRD
KPCG_HUMANSDC2_HUMANkinase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04514Cell adhesion molecules (CAMs)
hsa04512ECM-receptor interaction
hsa05144Malaria

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030165PDZ domain bindingIPImolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0005975carbohydrate metabolic processTASbiological_process
GO:0048814regulation of dendrite morphogenesisISSbiological_process
GO:0005887integral to plasma membraneNAScellular_component
GO:0048813dendrite morphogenesisIEAbiological_process
GO:0008092cytoskeletal protein bindingIEAmolecular_function
GO:0031000response to caffeineIEAbiological_process
GO:0006027glycosaminoglycan catabolic processTASbiological_process
GO:0030203glycosaminoglycan metabolic processTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0030204chondroitin sulfate metabolic processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0043202lysosomal lumenTAScellular_component
GO:0042060wound healingIEAbiological_process
GO:0043025neuronal cell bodyIEAcellular_component
GO:0001666response to hypoxiaIEAbiological_process
GO:0005796Golgi lumenTAScellular_component
GO:0006024glycosaminoglycan biosynthetic processTASbiological_process
GO:0008150biological_processNDbiological_process
GO:0016020membraneIEAcellular_component
GO:0005515protein bindingIPImolecular_function