Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:SCTR_HUMAN
Description:secretin receptor [Source:HGNC Symbol;Acc:10608]
Location:chr2 q14.2
Node attribute:GPCR; receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S420PVASFsNSTKAPhosphoSitePlus
Y146KLKVMyTVGYS7tm_2; TMPhosphoSitePlus
S418LHPVAsFSNSTPhosphoSitePlus
S422ASFSNsTKASHPhosphoSitePlus
T423SFSNStKASHLPhosphoSitePlus

Dephosphorylation site
SCTR_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000019103W112CCOSMICOvarian Cancer21720365
ENSP00000019103D196NCOSMICCentral Nervous System Neoplasms21163964

Differential expressed protein
SCTR_HUMAN is not differential expressed protein.

Hyperphosphorylation site
SCTR_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SECR_HUMANSCTR_HUMANligand -> receptorHPMR
SCTR_HUMANGNAS1_HUMANGPCR -> GproteingpDB
SCTR_HUMANGNAS2_HUMANGPCR -> GproteingpDB
GLHA_HUMANSCTR_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction
hsa04972Pancreatic secretion
hsa04976Bile secretion

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneTAScellular_component
GO:0007586digestionTASbiological_process
GO:0007166cell surface receptor signaling pathwayIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0015055secretin receptor activityTASmolecular_function
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0004888transmembrane signaling receptor activityIEAmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayTASbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0007588excretionTASbiological_process


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