| UniProt/SwissProt ID: | RSPO1_HUMAN |
| Description: | R-spondin 1 [Source:HGNC Symbol;Acc:21679] |
| Location: | chr1 p34.3 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T253 | QQQQGtVGPLT | PhosphoSitePlus | |
| Dephosphorylation site |
| RSPO1_HUMAN do not have dephosphorylation site. |
| Mutation site |
| RSPO1_HUMAN do not have mutation site. |
| Differential expressed protein |
| RSPO1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RSPO1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| RSPO1_HUMAN | LGR4_HUMAN | ligand -> receptor | HPMR |
| RSPO1_HUMAN | LRP6_HUMAN | ligand -> receptor | HPMR |
| RSPO1_HUMAN | LGR5_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| RSPO1_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0002090 | regulation of receptor internalization | IDA | biological_process |
| GO:0090263 | positive regulation of canonical Wnt receptor sign | IDA | biological_process |
| GO:0060070 | canonical Wnt receptor signaling pathway | IEA | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0005615 | extracellular space | IEA | cellular_component |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0008201 | heparin binding | IEA | molecular_function |
| GO:0005102 | receptor binding | IEA | molecular_function |
| GO:0030177 | positive regulation of Wnt receptor signaling path | IDA | biological_process |