| UniProt/SwissProt ID: | RHOJ_HUMAN |
| Description: | ras homolog family member J [Source:HGNC Symbol;Acc:688] |
| Location: | chr14 q23.2 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T7 | NCKEGtDSSCG | PhosphoSitePlus | |
| Dephosphorylation site |
| RHOJ_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000316729 | D56E | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000316729 | E49K | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| RHOJ_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RHOJ_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GBG10_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBB3_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBB1_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBG13_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBB5_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBG2_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBG11_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBG5_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBB2_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBG8_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBG12_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBG1_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| GBG3_HUMAN | RHOJ_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| RHOJ_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003924 | GTPase activity | NAS | molecular_function |
| GO:0015031 | protein transport | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0030036 | actin cytoskeleton organization | IEA | biological_process |
| GO:0051056 | regulation of small GTPase mediated signal transdu | TAS | biological_process |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0006184 | GTP catabolic process | NAS | biological_process |
| GO:0008360 | regulation of cell shape | IEA | biological_process |
| GO:0007266 | Rho protein signal transduction | IEA | biological_process |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005575 | cellular_component | ND | cellular_component |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0007264 | small GTPase mediated signal transduction | TAS | biological_process |
| GO:0030036 | actin cytoskeleton organization | IMP | biological_process |