| UniProt/SwissProt ID: | RHOF_HUMAN |
| Description: | ras homolog family member F (in filopodia) [Source:HGNC Symbol;Acc:15703] |
| Location: | chr12 q24.31 |
| Node attribute: | effector |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T10 | GALAQtAAPGP | PhosphoSitePlus; HPRD | |
| Y48 | SFPEHyAPSVF | Ras | PhosphoSitePlus |
| T74 | LNLYDtAGQED | Ras | PhosphoSitePlus |
| Y80 | AGQEDyDRLRP | Ras | PhosphoSitePlus |
| Y72 | VTLNLyDTAGQ | Ras | PhosphoSitePlus |
| S51 | EHYAPsVFEKY | Ras | PhosphoSitePlus |
| Dephosphorylation site |
| RHOF_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000267205 | S194R | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| RHOF_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| RHOF_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| GBG3_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBG5_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBG11_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBG2_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBB1_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBG12_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBB5_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBG13_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBB2_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBG8_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBG10_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBG1_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| GBB3_HUMAN | RHOF_HUMAN | Gprotein -> effector | gpDB |
| Function Annotation |
| KEGG Pathway |
| RHOF_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005886 | plasma membrane | TAS | cellular_component |
| GO:0007015 | actin filament organization | IDA | biological_process |
| GO:0015031 | protein transport | IEA | biological_process |
| GO:0006886 | intracellular protein transport | IEA | biological_process |
| GO:0051056 | regulation of small GTPase mediated signal transdu | TAS | biological_process |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0007264 | small GTPase mediated signal transduction | TAS | biological_process |
| GO:0006913 | nucleocytoplasmic transport | IEA | biological_process |
| GO:0005525 | GTP binding | IEA | molecular_function |
| GO:0005856 | cytoskeleton | NAS | cellular_component |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0007165 | signal transduction | IEA | biological_process |
| GO:0003924 | GTPase activity | NAS | molecular_function |
| GO:0006184 | GTP catabolic process | NAS | biological_process |