Phosphorylation

Ensembl ID	Cancer name	Design	Sample	Change	Ratio	Pubmed
ENSP00000360522	Hepatocellular Carcinoma	Normal vs. Cancer	tissue	Up	16	14654528
ENSP00000360522	Brain Cancer	Normal vs. Cancer	tissue	Up	4.5	18056677
ENSP00000360522	Pancreatic Cancer	Normal vs. Cancer	tissue	Up	3.3	16230073

Hyperphosphorylation site

RET4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair

Source	Target	Relationship	Resource
SP1_HUMAN	RET4_HUMAN	TF -> target gene	TRANSFAC
RARB_HUMAN	RET4_HUMAN	TF -> target gene	TRANSFAC
RXRA_HUMAN	RET4_HUMAN	TF -> target gene	TRANSFAC

Function Annotation

KEGG Pathway

RET4_HUMAN is not in KEGG pathway.

Gene Ontology

GO ID	GO_Term	Evidence	Ontology
GO:0042572	retinol metabolic process	IMP	biological_process
GO:0060347	heart trabecula formation	IEA	biological_process
GO:0034632	retinol transporter activity	IC	molecular_function
GO:0032526	response to retinoic acid	IDA	biological_process
GO:0034633	retinol transport	IC	biological_process
GO:0006094	gluconeogenesis	IEA	biological_process
GO:0007507	heart development	IEA	biological_process
GO:0019841	retinol binding	IDA	molecular_function
GO:0048738	cardiac muscle tissue development	ISS	biological_process
GO:0050908	detection of light stimulus involved in visual per	IEA	biological_process
GO:0043234	protein complex	IEA	cellular_component
GO:0030324	lung development	ISS	biological_process
GO:0001654	eye development	IEA	biological_process
GO:0001654	eye development	ISS	biological_process
GO:0060068	vagina development	IEA	biological_process
GO:0060041	retina development in camera-type eye	IEA	biological_process
GO:0048807	female genitalia morphogenesis	ISS	biological_process
GO:0032024	positive regulation of insulin secretion	IMP	biological_process
GO:0007507	heart development	ISS	biological_process
GO:0008584	male gonad development	IEA	biological_process
GO:0005615	extracellular space	ISS	cellular_component
GO:0048562	embryonic organ morphogenesis	IEA	biological_process
GO:0060157	urinary bladder development	ISS	biological_process
GO:0042574	retinal metabolic process	IEA	biological_process
GO:0060068	vagina development	ISS	biological_process
GO:0034632	retinol transporter activity	IEA	molecular_function
GO:0048738	cardiac muscle tissue development	IEA	biological_process
GO:0016918	retinal binding	IEA	molecular_function
GO:0042593	glucose homeostasis	IDA	biological_process
GO:0060157	urinary bladder development	IEA	biological_process
GO:0005615	extracellular space	IEA	cellular_component
GO:0046982	protein heterodimerization activity	IEA	molecular_function
GO:0032868	response to insulin stimulus	IEA	biological_process
GO:0045471	response to ethanol	IEA	biological_process
GO:0042572	retinol metabolic process	IEA	biological_process
GO:0006094	gluconeogenesis	ISS	biological_process
GO:0009790	embryo development	IEA	biological_process
GO:0060065	uterus development	IEA	biological_process
GO:0048706	embryonic skeletal system development	IEA	biological_process
GO:0060059	embryonic retina morphogenesis in camera-type eye	IEA	biological_process
GO:0048562	embryonic organ morphogenesis	ISS	biological_process
GO:0019841	retinol binding	IEA	molecular_function
GO:0060044	negative regulation of cardiac muscle cell prolife	IEA	biological_process
GO:0030277	maintenance of gastrointestinal epithelium	IDA	biological_process
GO:0060347	heart trabecula formation	ISS	biological_process
GO:0051024	positive regulation of immunoglobulin secretion	IEA	biological_process
GO:0051024	positive regulation of immunoglobulin secretion	ISS	biological_process
GO:0048807	female genitalia morphogenesis	IEA	biological_process
GO:0034633	retinol transport	IEA	biological_process
GO:0007283	spermatogenesis	IEA	biological_process
GO:0005515	protein binding	IPI	molecular_function
GO:0060065	uterus development	ISS	biological_process
GO:0060044	negative regulation of cardiac muscle cell prolife	ISS	biological_process
GO:0048706	embryonic skeletal system development	ISS	biological_process
GO:0060059	embryonic retina morphogenesis in camera-type eye	ISS	biological_process
GO:0030324	lung development	IEA	biological_process

Human Phosphorylation Mediated
Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated Signaling Transduction Network

PhoSigNet

Human Phosphorylation Mediated
Signaling Transduction Network