Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RBX2_HUMAN
Description:ring finger protein 7 [Source:HGNC Symbol;Acc:10070]
Location:chr3 q23
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T10EDGEEtCALASP67870(Casein kinase II )RegPhos
S15TCALAsHSGSSPhosphoSitePlus
T10EDGEEtCALASCSNK2BHPRD
T10EDGEEtCALASCK2_alphaphosphoELM
S31GDKMFsLKKWNzf-rbx1PhosphoSitePlus
T10EDGEEtCALASPhosphoSitePlus
T10EDGEEtCALASCK2a1(CK2 alphaRegPhos
T10EDGEEtCALASCK2_groupphosphoELM; RegPhos

Dephosphorylation site
RBX2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000273480E79QCOSMICHead and Neck Cancer21798893

Differential expressed protein
RBX2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RBX2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CSK2B_HUMANRBX2_HUMANkinase -> substrateHPRD
CSK21_HUMANRBX2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04120Ubiquitin mediated proteolysis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043066negative regulation of apoptotic processTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0051775response to redox stateTASbiological_process
GO:0008270zinc ion bindingIEAmolecular_function
GO:0008631intrinsic apoptotic signaling pathway in response TASbiological_process
GO:0019788NEDD8 ligase activityIDAmolecular_function
GO:0045116protein neddylationIDAbiological_process
GO:0005507copper ion bindingTASmolecular_function
GO:0016567protein ubiquitinationIEAbiological_process
GO:0031466Cul5-RING ubiquitin ligase complexIDAcellular_component


Fatal error: Uncaught Error: Call to undefined function mysql_close() in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php:23 Stack trace: #0 /usr/local/apache/htdocs/PhoSigNet/proteintable.php(435): db_disconnect(Object(mysqli)) #1 {main} thrown in /usr/local/apache/htdocs/PhoSigNet/include/locateconfig.inc.php on line 23