Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:RAB5B_HUMAN
Description:RAB5B, member RAS oncogene family [Source:HGNC Symbol;Acc:9784]
Location:chr12 q13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y82AGQERyHSLAPRasPhosphoSitePlus
S123LQRQAsPSIVIRasPhosphoSitePlus
S123LQRQAsPSIVICDC2(CDK1RegPhos
S123LQRQAsPSIVICDC2RegPhos
S123LQRQAsPSIVICDK1HPRD; phosphoELM
S84QERYHsLAPMYRasPhosphoSitePlus

Dephosphorylation site
RAB5B_HUMAN do not have dephosphorylation site.

Mutation site
RAB5B_HUMAN do not have mutation site.

Differential expressed protein
RAB5B_HUMAN is not differential expressed protein.

Hyperphosphorylation site
RAB5B_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FAK2_HUMANRAB5B_HUMANkinase -> substrateRobert H Newman (2013)
CDK1_HUMANRAB5B_HUMANkinase -> substrateHPRD; RegPhos
KS6B1_HUMANRAB5B_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04145Phagosome
hsa05146Amoebiasis
hsa05152Tuberculosis
hsa04962Vasopressin-regulated water reabsorption
hsa04144Endocytosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005525GTP bindingIEAmolecular_function
GO:0007264small GTPase mediated signal transductionIEAbiological_process
GO:0006913nucleocytoplasmic transportIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0005622intracellularIDAcellular_component
GO:0006184GTP catabolic processTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0019003GDP bindingIDAmolecular_function
GO:0030139endocytic vesicleIEAcellular_component
GO:0030100regulation of endocytosisIEAbiological_process
GO:0007165signal transductionIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0016020membraneTAScellular_component
GO:0030742GTP-dependent protein bindingIDAmolecular_function
GO:0015031protein transportIEAbiological_process
GO:0031901early endosome membraneIEAcellular_component
GO:0005737cytoplasmIEAcellular_component
GO:0005768endosomeIDAcellular_component
GO:0007032endosome organizationIEAbiological_process
GO:0042470melanosomeIEAcellular_component
GO:0006886intracellular protein transportIEAbiological_process
GO:0003924GTPase activityTASmolecular_function


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