Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PRKX_HUMAN
Description:protein kinase, X-linked [Source:HGNC Symbol;Acc:9441]
Location:chrX p22.33
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S305HRWFRsVDWEAPhosphoSitePlus
T201KLVDRtWTLCGPkinase_AGCPhosphoSitePlus
T203VDRTWtLCGTPPkinase_AGCPhosphoSitePlus

Dephosphorylation site
PRKX_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000262848H299LDing2008, BIOMARTLung Cancer18948947, 21930507, 21930502
ENSP00000262848V94IBIOMARTPancreatic Cancer21930507, 21930502

Differential expressed protein
PRKX_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PRKX_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
PRKX_HUMANKAP0_HUMANkinase -> substrateRobert H Newman (2013)
PRKX_HUMANKAPCB_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
PRKX_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0043542endothelial cell migrationIMPbiological_process
GO:0060562epithelial tube morphogenesisIDAbiological_process
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0006468protein phosphorylationIEAbiological_process
GO:0004672protein kinase activityIEAmolecular_function
GO:0007155cell adhesionIEAbiological_process
GO:2000696regulation of epithelial cell differentiation invoIDAbiological_process
GO:0030334regulation of cell migrationIDAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0031589cell-substrate adhesionIMPbiological_process
GO:0018105peptidyl-serine phosphorylationIDAbiological_process
GO:0004691cAMP-dependent protein kinase activityIDAmolecular_function
GO:0046777protein autophosphorylationIDAbiological_process
GO:0007155cell adhesionIMPbiological_process
GO:0030099myeloid cell differentiationIDAbiological_process
GO:0030155regulation of cell adhesionIDAbiological_process
GO:0060993kidney morphogenesisIDAbiological_process
GO:0001935endothelial cell proliferationIMPbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0005737cytoplasmIDAcellular_component
GO:0005634nucleusIDAcellular_component
GO:0042802identical protein bindingIPImolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function
GO:0001525angiogenesisIMPbiological_process


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