| UniProt/SwissProt ID: | PPIP1_HUMAN |
| Description: | proline-serine-threonine phosphatase interacting protein 1 [Source:HGNC Symbol;Acc:9580] |
| Location: | chr15 q24.3 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S140 | KKAMEsKKTYE | PhosphoSitePlus | |
| S173 | KQVEKsQNKAR | PhosphoSitePlus | |
| Y119 | EQRKKyEAVMD | PhosphoSitePlus | |
| Y345 | RNEGVyTAIAV | ABL1 | HPRD; RegPhos |
| Y345 | RNEGVyTAIAV | Abl | phosphoELM |
| Dephosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y345 | PERNEGVyTAIAVQE | PTPN12 | HPRD |
| Mutation site |
| PPIP1_HUMAN do not have mutation site. |
| Differential expressed protein |
| PPIP1_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PPIP1_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ABL1_HUMAN | PPIP1_HUMAN | kinase -> substrate | HPRD; RegPhos |
| PTN12_HUMAN | PPIP1_HUMAN | phosphatase -> substrate | HPRD |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04621 | NOD-like receptor signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0016491 | oxidoreductase activity | IEA | molecular_function |
| GO:0007155 | cell adhesion | IEA | biological_process |
| GO:0048471 | perinuclear region of cytoplasm | IEA | cellular_component |
| GO:0055114 | oxidation-reduction process | IEA | biological_process |
| GO:0019903 | protein phosphatase binding | IEA | molecular_function |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0003779 | actin binding | IEA | molecular_function |
| GO:0005826 | actomyosin contractile ring | IEA | cellular_component |
| GO:0045087 | innate immune response | TAS | biological_process |
| GO:0035872 | nucleotide-binding domain, leucine rich repeat con | TAS | biological_process |
| GO:0001725 | stress fiber | IEA | cellular_component |
| GO:0032154 | cleavage furrow | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0003824 | catalytic activity | IEA | molecular_function |
| GO:0030027 | lamellipodium | IEA | cellular_component |