| UniProt/SwissProt ID: | PPA6_HUMAN |
| Description: | acid phosphatase 6, lysophosphatidic [Source:HGNC Symbol;Acc:29609] |
| Location: | chr1 q21.2 |
| Node attribute: | ligand |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S296 | KEDREsLQMAV | Acid_phosphat_A | PhosphoSitePlus |
| S229 | LQPGIsEDLKK | Acid_phosphat_A | PhosphoSitePlus |
| S223 | RRQTAsLQPGI | Acid_phosphat_A | PhosphoSitePlus |
| Dephosphorylation site |
| PPA6_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000358241 | K236E | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| PPA6_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| PPA6_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| PPA6_HUMAN | S1PR1_HUMAN | ligand -> receptor | HPMR |
| PPA6_HUMAN | LPAR1_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa00740 | Riboflavin metabolism |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003993 | acid phosphatase activity | IEA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005739 | mitochondrion | IEA | cellular_component |
| GO:0006629 | lipid metabolic process | TAS | biological_process |
| GO:0005576 | extracellular region | IEA | cellular_component |