Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:PD2R_HUMAN
Description:prostaglandin D2 receptor (DP) [Source:HGNC Symbol;Acc:9591]
Location:chr14 q22.1
Node attribute:GPCR; receptor; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S254DGREAsPQPLE7tm_1PhosphoSitePlus
S352SRCSNsTNMESPhosphoSitePlus
S358TNMESsL____PhosphoSitePlus
S357STNMEsSL___PhosphoSitePlus
T353RCSNStNMESSPhosphoSitePlus

Dephosphorylation site
PD2R_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000303424Y226HCOSMICLung Cancer20668451
ENSP00000303424W131LCOSMICOvarian Cancer21720365
ENSP00000303424S119WCOSMICHead and Neck Cancer21798893
ENSP00000303424W131LTCGAOvarian Cancer21720365, 18772890
ENSP00000303424E190KCOSMICMelanoma21499247

Differential expressed protein
PD2R_HUMAN is not differential expressed protein.

Hyperphosphorylation site
PD2R_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
HPGDS_HUMANPD2R_HUMANligand -> receptorHPMR
PD2R_HUMANGNAS2_HUMANGPCR -> GproteingpDB
PD2R_HUMANGNAS1_HUMANGPCR -> GproteingpDB
GLHA_HUMANPD2R_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030238male sex determinationIEAbiological_process
GO:0006954inflammatory responseIEAbiological_process
GO:0046085adenosine metabolic processIEAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0007186G-protein coupled receptor signaling pathwayNASbiological_process
GO:0004956prostaglandin D receptor activityIEAmolecular_function
GO:0016021integral to membraneNAScellular_component
GO:0005886plasma membraneIDAcellular_component
GO:0005886plasma membraneIEAcellular_component
GO:0001785prostaglandin J receptor activityIEAmolecular_function
GO:0071799cellular response to prostaglandin D stimulusIEAbiological_process
GO:0004956prostaglandin D receptor activityNASmolecular_function
GO:0030431sleepIEAbiological_process
GO:0005515protein bindingIPImolecular_function


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