| UniProt/SwissProt ID: | HPGDS_HUMAN |
| Description: | hematopoietic prostaglandin D synthase [Source:HGNC Symbol;Acc:17890] |
| Location: | chr4 q22.3 |
| Node attribute: | ligand |
| Phosphorylation site |
| HPGDS_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| HPGDS_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000295256 | L54fs*12 | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| HPGDS_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| HPGDS_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| HPGDS_HUMAN | PD2R_HUMAN | ligand -> receptor | HPMR |
| HPGDS_HUMAN | PD2R2_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa01100 | Metabolic pathways |
| hsa00590 | Arachidonic acid metabolism |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007626 | locomotory behavior | TAS | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0007165 | signal transduction | NAS | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0001516 | prostaglandin biosynthetic process | IEA | biological_process |
| GO:0004667 | prostaglandin-D synthase activity | IEA | molecular_function |
| GO:0004667 | prostaglandin-D synthase activity | IDA | molecular_function |
| GO:0042803 | protein homodimerization activity | IPI | molecular_function |
| GO:0005509 | calcium ion binding | IDA | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0006693 | prostaglandin metabolic process | IDA | biological_process |
| GO:0004364 | glutathione transferase activity | IEA | molecular_function |
| GO:0000287 | magnesium ion binding | IDA | molecular_function |
| GO:0006693 | prostaglandin metabolic process | IEA | biological_process |