| UniProt/SwissProt ID: | ZN267_HUMAN |
| Description: | zinc finger protein 267 [Source:HGNC Symbol;Acc:13060] |
| Location: | chr16 p11.2 |
| Node attribute: | gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S201 | LFRQVsTLNSY | PhosphoSitePlus | |
| Y520 | TGENLyKCKVC | HPRD; phosphoELM | |
| S194 | IYDKTsVLFRQ | PhosphoSitePlus | |
| T543 | HERIHtGEKPY | PhosphoSitePlus | |
| T597 | TVHRRtHTGEK | zf-C2H2; C1_4 | PhosphoSitePlus |
| T424 | CSSYLtKHKRI | HPRD; phosphoELM; SysPTM | |
| Y615 | GKAFSySSDVI | C1_4; zf-C2H2 | PhosphoSitePlus |
| Y688 | TGERPyKCDEC | zf-C2H2 | PhosphoSitePlus |
| T403 | HQRIHtGEKPY | PhosphoSitePlus | |
| T655 | HQRSHtGERPY | PhosphoSitePlus | |
| Y699 | GKAFSyRSYLT | zf-C2H2 | PhosphoSitePlus |
| T431 | HKRIHtGEKPY | PhosphoSitePlus | |
| Y520 | TGENLyKCKVC | zf-C2H2 | PhosphoSitePlus |
| T571 | HHRIHtGEKPY | Zn_Tnp_IS1595 | PhosphoSitePlus |
| T599 | HRRTHtGEKPY | C1_4 | PhosphoSitePlus |
| T54 | KPDLItFLEQR | PhosphoSitePlus | |
| S653 | TTHQRsHTGER | zf-C2H2 | PhosphoSitePlus |
| T487 | HQRVHtGEKPY | PhosphoSitePlus | |
| Dephosphorylation site |
| ZN267_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000300870 | I536M | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000300870 | S560T | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000300870 | S100L | COSMIC | Skin Cancer | 21984974 | ENSP00000300870 | K312E | COSMIC | Breast Cancer | 17932254 | ENSP00000300870 | K49N | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000300870 | S560T | COSMIC | Ovarian Cancer | 21720365 | ENSP00000300870 | A640V | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000300870 | S393F | COSMIC | Skin Cancer | 21984974 | ENSP00000300870 | A640V | COSMIC | Ovarian Cancer | 21720365 | ENSP00000300870 | L337V | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000300870 | Neoplasms by Histologic Type | Treatment (none vs. SB203580 treatment 3 hour) | cell line | Down | 0.66 | 15169874 |
| Hyperphosphorylation site |
| ZN267_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| NFYA_HUMAN | ZN267_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| ZN267_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0007275 | multicellular organismal development | TAS | biological_process |
| GO:0008270 | zinc ion binding | IEA | molecular_function |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0003676 | nucleic acid binding | IEA | molecular_function |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |