Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:NCBP2_HUMAN
Description:nuclear cap binding protein subunit 2, 20kDa [Source:HGNC Symbol;Acc:7659]
Location:chr3 q29
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y138QVRDEyRQDYDPhosphoSitePlus
Y57TEEQIyELFSKRRM_1PhosphoSitePlus
Y142EYRQDyDAGRGPhosphoSitePlus
S130YGRGRsGGQVRPhosphoSitePlus; HPRD
Y89CFVEYySRADARRM_1PhosphoSitePlus
S13ALRSDsYVELSPhosphoSitePlus
T79DKMKKtACGFCRRM_1PhosphoSitePlus
S18SYVELsQYRDQPhosphoSitePlus; HPRD; phosphoELM
Y14LRSDSyVELSQPhosphoSitePlus

Dephosphorylation site
NCBP2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000326806*157SCOSMICMelanoma9354451

Differential expressed protein
NCBP2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
NCBP2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
STK16_HUMANNCBP2_HUMANkinase -> substrateRobert H Newman (2013)
CDK7_HUMANNCBP2_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANNCBP2_HUMANkinase -> substrateRobert H Newman (2013)
KS6B1_HUMANNCBP2_HUMANkinase -> substrateRobert H Newman (2013)
CLK2_HUMANNCBP2_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
NCBP2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0046833positive regulation of RNA export from nucleusISSbiological_process
GO:0016071mRNA metabolic processTASbiological_process
GO:0000339RNA cap bindingNASmolecular_function
GO:0016070RNA metabolic processTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0045292mRNA cis splicing, via spliceosomeIDAbiological_process
GO:0006446regulation of translational initiationIDAbiological_process
GO:0006368transcription elongation from RNA polymerase II prTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0006406mRNA export from nucleusTASbiological_process
GO:0050434positive regulation of viral transcriptionTASbiological_process
GO:0000340RNA 7-methylguanosine cap bindingIDAmolecular_function
GO:0000387spliceosomal snRNP assemblyTASbiological_process
GO:0006397mRNA processingTASbiological_process
GO:0005634nucleusIDAcellular_component
GO:0016032viral reproductionTASbiological_process
GO:0034660ncRNA metabolic processTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:00063707-methylguanosine mRNA cappingIDAbiological_process
GO:0000166nucleotide bindingIEAmolecular_function
GO:0010467gene expressionTASbiological_process
GO:0008334histone mRNA metabolic processTASbiological_process
GO:0000398mRNA splicing, via spliceosomeTASbiological_process
GO:0006408snRNA export from nucleusISSbiological_process
GO:0006366transcription from RNA polymerase II promoterTASbiological_process
GO:0031124mRNA 3'-end processingTASbiological_process
GO:0005654nucleoplasmIDAcellular_component
GO:0008380RNA splicingISSbiological_process
GO:0006369termination of RNA polymerase II transcriptionTASbiological_process
GO:0000184nuclear-transcribed mRNA catabolic process, nonsenIDAbiological_process
GO:0005845mRNA cap binding complexIDAcellular_component
GO:0031047gene silencing by RNAIEAbiological_process
GO:0003676nucleic acid bindingIEAmolecular_function


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