| UniProt/SwissProt ID: | KCIP2_HUMAN |
| Description: | Kv channel interacting protein 2 [Source:HGNC Symbol;Acc:15522] |
| Location: | chr10 q24.32 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S207 | LDIMKsIYDMM | efhand | PhosphoSitePlus |
| Y209 | IMKSIyDMMGK | PhosphoSitePlus | |
| Y111 | ELQVLyRGFKN | PhosphoSitePlus; phosphoELM | |
| T24 | SYDQLtGHPPG | PhosphoSitePlus | |
| T31 | HPPGPtKKALK | PhosphoSitePlus | |
| T103 | EQTKFtRKELQ | PhosphoSitePlus; phosphoELM | |
| Dephosphorylation site |
| KCIP2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000239118 | *226Y | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| KCIP2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| KCIP2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ANPRB_HUMAN | KCIP2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| SIK1_HUMAN | KCIP2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| PRKY_HUMAN | KCIP2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| FAK2_HUMAN | KCIP2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| DYRK2_HUMAN | KCIP2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| NEK10_HUMAN | KCIP2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KPCA_HUMAN | KCIP2_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| KCIP2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0047485 | protein N-terminus binding | IPI | molecular_function |
| GO:0008016 | regulation of heart contraction | TAS | biological_process |
| GO:0007268 | synaptic transmission | NAS | biological_process |
| GO:0046923 | ER retention sequence binding | NAS | molecular_function |
| GO:0007165 | signal transduction | TAS | biological_process |
| GO:0006813 | potassium ion transport | TAS | biological_process |
| GO:0005250 | A-type (transient outward) potassium channel activ | TAS | molecular_function |
| GO:0005513 | detection of calcium ion | TAS | biological_process |
| GO:0045163 | clustering of voltage-gated potassium channels | IDA | biological_process |
| GO:0008076 | voltage-gated potassium channel complex | NAS | cellular_component |
| GO:0042802 | identical protein binding | IPI | molecular_function |
| GO:0005578 | proteinaceous extracellular matrix | IEA | cellular_component |
| GO:0006936 | muscle contraction | NAS | biological_process |
| GO:0005509 | calcium ion binding | TAS | molecular_function |
| GO:0005737 | cytoplasm | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |