Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IRK15_HUMAN
Description:potassium inwardly-rectifying channel, subfamily J, member 15 [Source:HGNC Symbol;Acc:6261]
Location:chr21 q22.13
Node attribute:effector

Phosphorylation site
IRK15_HUMAN do not have phosphorylation site.

Dephosphorylation site
IRK15_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000331698A71TSjoblom2006, HPIBreast Cancer16959974
ENSP00000381904K319*TCGA, COSMICOvarian Cancer21720365, 18772890
ENSP00000381904V29ICOSMICCentral Nervous System Neoplasms18772396
ENSP00000381904Y355FCOSMICOvarian Cancer21720365
ENSP00000381911A71TSjoblom2006, HPIBreast Cancer16959974
ENSP00000381904Y355FTCGAOvarian Cancer21720365, 18772890
ENSP00000381907Y355FTCGAOvarian Cancer21720365, 18772890
ENSP00000381904M76ICOSMICMelanoma21499247
ENSP00000381904A71TSjoblom2006, COSMIC, HPIBreast Cancer16959974
ENSP00000381911K319*TCGAOvarian Cancer21720365, 18772890
ENSP00000381907K319*TCGAOvarian Cancer21720365, 18772890
ENSP00000381907A71TSjoblom2006, HPI, BIOMARTBreast Cancer16959974, 21930507, 21930502
ENSP00000381905A71TSjoblom2006, HPIBreast Cancer16959974
ENSP00000331698K319*TCGAOvarian Cancer21720365, 18772890
ENSP00000381911Y355FTCGAOvarian Cancer21720365, 18772890
ENSP00000381905Y355FTCGAOvarian Cancer21720365, 18772890
ENSP00000381905K319*TCGAOvarian Cancer21720365, 18772890
ENSP00000331698Y355FTCGAOvarian Cancer21720365, 18772890

Differential expressed protein
IRK15_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IRK15_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GBG13_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBG10_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBG11_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBB2_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBG12_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBB3_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBG2_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBG5_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBB1_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBG1_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBB5_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBG3_HUMANIRK15_HUMANGprotein -> effectorgpDB
GBG8_HUMANIRK15_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04971Gastric acid secretion

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0006813potassium ion transportIEAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0007268synaptic transmissionTASbiological_process
GO:0016021integral to membraneIEAcellular_component
GO:0005267potassium channel activityIEAmolecular_function
GO:0006813potassium ion transportTASbiological_process
GO:0005242inward rectifier potassium channel activityIEAmolecular_function
GO:0071805potassium ion transmembrane transportIEAbiological_process
GO:0005887integral to plasma membraneTAScellular_component


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