| UniProt/SwissProt ID: | IRF2_HUMAN |
| Description: | interferon regulatory factor 2 [Source:HGNC Symbol;Acc:6117] |
| Location: | chr4 q35.1 |
| Node attribute: | TF |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S163 | YAVLTsTIKNE | HPRD | |
| S144 | EPVESsLGLSN | HPRD | |
| S148 | SSLGLsNGVSD | HPRD | |
| T164 | AVLTStIKNEV | HPRD | |
| T162 | EYAVLtSTIKN | HPRD | |
| S143 | QEPVEsSLGLS | HPRD | |
| Dephosphorylation site |
| IRF2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| IRF2_HUMAN do not have mutation site. |
| Differential expressed protein |
| IRF2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| IRF2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| IRF2_HUMAN | U627C_HUMAN | TF -> target gene | TRANSFAC |
| IRF2_HUMAN | IFNB_HUMAN | TF -> target gene | TRANSFAC |
| IRF2_HUMAN | IL12B_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| IRF2_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0003677 | DNA binding | IDA | molecular_function |
| GO:0019221 | cytokine-mediated signaling pathway | TAS | biological_process |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0060333 | interferon-gamma-mediated signaling pathway | TAS | biological_process |
| GO:0005634 | nucleus | IDA | cellular_component |
| GO:0005925 | focal adhesion | IDA | cellular_component |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0060337 | type I interferon-mediated signaling pathway | TAS | biological_process |
| GO:0000975 | regulatory region DNA binding | IEA | molecular_function |
| GO:0007596 | blood coagulation | TAS | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | IEA | molecular_function |
| GO:0005654 | nucleoplasm | TAS | cellular_component |
| GO:0000122 | negative regulation of transcription from RNA poly | TAS | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0006355 | regulation of transcription, DNA-dependent | IMP | biological_process |
| GO:0008283 | cell proliferation | TAS | biological_process |