Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IRF2_HUMAN
Description:interferon regulatory factor 2 [Source:HGNC Symbol;Acc:6117]
Location:chr4 q35.1
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S163YAVLTsTIKNEHPRD
S144EPVESsLGLSNHPRD
S148SSLGLsNGVSDHPRD
T164AVLTStIKNEVHPRD
T162EYAVLtSTIKNHPRD
S143QEPVEsSLGLSHPRD

Dephosphorylation site
IRF2_HUMAN do not have dephosphorylation site.

Mutation site
IRF2_HUMAN do not have mutation site.

Differential expressed protein
IRF2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IRF2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
IRF2_HUMANU627C_HUMANTF -> target geneTRANSFAC
IRF2_HUMANIFNB_HUMANTF -> target geneTRANSFAC
IRF2_HUMANIL12B_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
IRF2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0003677DNA bindingIDAmolecular_function
GO:0019221cytokine-mediated signaling pathwayTASbiological_process
GO:0005829cytosolTAScellular_component
GO:0060333interferon-gamma-mediated signaling pathwayTASbiological_process
GO:0005634nucleusIDAcellular_component
GO:0005925focal adhesionIDAcellular_component
GO:0005515protein bindingIPImolecular_function
GO:0060337type I interferon-mediated signaling pathwayTASbiological_process
GO:0000975regulatory region DNA bindingIEAmolecular_function
GO:0007596blood coagulationTASbiological_process
GO:0003700sequence-specific DNA binding transcription factorIEAmolecular_function
GO:0005654nucleoplasmTAScellular_component
GO:0000122negative regulation of transcription from RNA polyTASbiological_process
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIMPbiological_process
GO:0008283cell proliferationTASbiological_process


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