| UniProt/SwissProt ID: | INVO_HUMAN |
| Description: | involucrin [Source:HGNC Symbol;Acc:6187] |
| Location: | chr1 q21.3 |
| Node attribute: | gene |
| Phosphorylation site |
| INVO_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| INVO_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000357753 | E102A | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000357753 | M280L | TCGA | Ovarian Cancer | 21720365, 18772890 |
| Differential expressed protein |
| INVO_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| INVO_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| SP1_HUMAN | INVO_HUMAN | TF -> target gene | TRANSFAC |
| PO2F1_HUMAN | INVO_HUMAN | TF -> target gene | TRANSFAC |
| JUND_HUMAN | INVO_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| INVO_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0031424 | keratinization | IEA | biological_process |
| GO:0018149 | peptide cross-linking | IDA | biological_process |
| GO:0030216 | keratinocyte differentiation | IDA | biological_process |
| GO:0005198 | structural molecule activity | IDA | molecular_function |
| GO:0030674 | protein binding, bridging | IDA | molecular_function |
| GO:0010224 | response to UV-B | IDA | biological_process |
| GO:0018153 | isopeptide cross-linking via N6-(L-isoglutamyl)-L- | TAS | biological_process |
| GO:0001533 | cornified envelope | IEA | cellular_component |
| GO:0005737 | cytoplasm | IEA | cellular_component |