Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:INHBA_HUMAN
Description:inhibin, beta A [Source:HGNC Symbol;Acc:6066]
Location:chr7 p14.1
Node attribute:PPI(target); ligand; PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y404MSMLYyDDGQNTGF_betaPhosphoSitePlus
S226FPVSSsIQRLLTGFb_propeptidePhosphoSitePlus

Dephosphorylation site
INHBA_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000242208E151*Ding2008, COSMICLung Cancer18948947
ENSP00000242208V420MCOSMICOvarian Cancer21720365
ENSP00000242208P22HDing2008, COSMICLung Cancer18948947
ENSP00000242208D232YDing2008, COSMICLung Cancer18948947
ENSP00000242208R201SDing2008, COSMICLung Cancer18948947
ENSP00000242208R306PCOSMICHead and Neck Cancer21798893

Differential expressed protein
INHBA_HUMAN is not differential expressed protein.

Hyperphosphorylation site
INHBA_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
INHBA_HUMANAVR2A_HUMANligand -> receptorHPMR
INHBA_HUMANACV1B_HUMANligand -> receptorHPMR
INHBA_HUMANTGFB1_HUMANotherKEGG
INHBA_HUMANAVR2A_HUMANotherKEGG
FST_HUMANINHBA_HUMANotherKEGG
INHBA_HUMANNODAL_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04060Cytokine-cytokine receptor interaction
hsa04350TGF-beta signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0017046peptide hormone bindingIPImolecular_function
GO:0061029eyelid development in camera-type eyeISSbiological_process
GO:0007050cell cycle arrestIDAbiological_process
GO:0008285negative regulation of cell proliferationIDAbiological_process
GO:0042476odontogenesisIGIbiological_process
GO:0006917induction of apoptosisIDAbiological_process
GO:0042326negative regulation of phosphorylationTASbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIEAbiological_process
GO:0005179hormone activityTASmolecular_function
GO:0030154cell differentiationTASbiological_process
GO:0045648positive regulation of erythrocyte differentiationIDAbiological_process
GO:0071397cellular response to cholesterolIEAbiological_process
GO:0042802identical protein bindingIPImolecular_function
GO:0042541hemoglobin biosynthetic processIDAbiological_process
GO:0045650negative regulation of macrophage differentiationTASbiological_process
GO:0045578negative regulation of B cell differentiationTASbiological_process
GO:0005576extracellular regionIDAcellular_component
GO:0060279positive regulation of ovulationISSbiological_process
GO:0043512inhibin A complexIDAcellular_component
GO:0001942hair follicle developmentIGIbiological_process
GO:0070699type II activin receptor bindingIPImolecular_function
GO:0008584male gonad developmentIGIbiological_process
GO:0007399nervous system developmentNASbiological_process
GO:0005125cytokine activityIDAmolecular_function
GO:0010862positive regulation of pathway-restricted SMAD proIDAbiological_process
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0045944positive regulation of transcription from RNA polyIEAbiological_process
GO:0002244hematopoietic progenitor cell differentiationIEAbiological_process
GO:0006952defense responseTASbiological_process
GO:0046982protein heterodimerization activityIEAmolecular_function
GO:0071372cellular response to follicle-stimulating hormone IEAbiological_process
GO:0000082G1/S transition of mitotic cell cycleIDAbiological_process
GO:0008083growth factor activityTASmolecular_function
GO:0048333mesodermal cell differentiationIEAbiological_process
GO:0046880regulation of follicle-stimulating hormone secretiIGIbiological_process
GO:0005102receptor bindingIEAmolecular_function
GO:0001541ovarian follicle developmentIGIbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0032925regulation of activin receptor signaling pathwayIDAbiological_process
GO:0030218erythrocyte differentiationNASbiological_process
GO:0043509activin A complexIDAcellular_component
GO:0060279positive regulation of ovulationIEAbiological_process
GO:0045786negative regulation of cell cycleIDAbiological_process
GO:0006357regulation of transcription from RNA polymerase IIIDAbiological_process
GO:0061029eyelid development in camera-type eyeIEAbiological_process
GO:0060021palate developmentIGIbiological_process
GO:0030308negative regulation of cell growthIDAbiological_process
GO:0045077negative regulation of interferon-gamma biosynthetTASbiological_process
GO:0042701progesterone secretionIGIbiological_process
GO:0007267cell-cell signalingTASbiological_process
GO:0046882negative regulation of follicle-stimulating hormonNASbiological_process
GO:0043512inhibin A complexIEAcellular_component
GO:0046881positive regulation of follicle-stimulating hormonTASbiological_process
GO:0002244hematopoietic progenitor cell differentiationIDAbiological_process
GO:0040007growthIEAbiological_process
GO:0001707mesoderm formationIEAbiological_process