Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IL12A_HUMAN
Description:interleukin 12A (natural killer cell stimulatory factor 1, cytotoxic lymphocyte maturation factor 1, p35) [Source:HGNC Symbol;Acc:5969]
Location:chr3 q25.33
Node attribute:PPI(target)

Phosphorylation site
IL12A_HUMAN do not have phosphorylation site.

Dephosphorylation site
IL12A_HUMAN do not have dephosphorylation site.

Mutation site
IL12A_HUMAN do not have mutation site.

Differential expressed protein
IL12A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IL12A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NFKB1_HUMANIL12A_HUMANotherKEGG
FOS_HUMANIL12A_HUMANotherKEGG
IRF5_HUMANIL12A_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05145Toxoplasmosis
hsa05162Measles
hsa05164Influenza A
hsa05133Pertussis
hsa04940Type I diabetes mellitus
hsa05330Allograft rejection
hsa05143African trypanosomiasis
hsa04622RIG-I-like receptor signaling pathway
hsa04060Cytokine-cytokine receptor interaction
hsa05142Chagas disease (American trypanosomiasis)
hsa05144Malaria
hsa05140Leishmaniasis
hsa05146Amoebiasis
hsa05168Herpes simplex infection
hsa04620Toll-like receptor signaling pathway
hsa04630Jak-STAT signaling pathway
hsa05152Tuberculosis
hsa05134Legionellosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0042102positive regulation of T cell proliferationIEAbiological_process
GO:0005125cytokine activityTASmolecular_function
GO:0043514interleukin-12 complexIEAcellular_component
GO:0050671positive regulation of lymphocyte proliferationIDAbiological_process
GO:0046982protein heterodimerization activityIPImolecular_function
GO:0042163interleukin-12 beta subunit bindingIEAmolecular_function
GO:0007050cell cycle arrestIDAbiological_process
GO:0002860positive regulation of natural killer cell mediateIDAbiological_process
GO:0045785positive regulation of cell adhesionIDAbiological_process
GO:0010224response to UV-BIDAbiological_process
GO:0042832defense response to protozoanIEAbiological_process
GO:0032496response to lipopolysaccharideIDAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0050830defense response to Gram-positive bacteriumIEPbiological_process
GO:0009615response to virusIEPbiological_process
GO:0042520positive regulation of tyrosine phosphorylation ofIDAbiological_process
GO:0034393positive regulation of smooth muscle cell apoptotiIDAbiological_process
GO:0045513interleukin-27 bindingIPImolecular_function
GO:0001916positive regulation of T cell mediated cytotoxicitIDAbiological_process
GO:0048662negative regulation of smooth muscle cell proliferIDAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0032816positive regulation of natural killer cell activatIDAbiological_process
GO:0051135positive regulation of NK T cell activationIDAbiological_process
GO:0032729positive regulation of interferon-gamma productionIEAbiological_process
GO:0032729positive regulation of interferon-gamma productionIDAbiological_process
GO:0005125cytokine activityIEAmolecular_function
GO:0016477cell migrationIDAbiological_process
GO:0008083growth factor activityNASmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0043514interleukin-12 complexIDAcellular_component
GO:0005576extracellular regionIEAcellular_component
GO:0006955immune responseTASbiological_process
GO:0005143interleukin-12 receptor bindingNASmolecular_function
GO:0045954positive regulation of natural killer cell mediateIDAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0032700negative regulation of interleukin-17 productionIDAbiological_process