Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:IGF2_HUMAN
Description:insulin-like growth factor 2 (somatomedin A) [Source:HGNC Symbol;Acc:5466]
Location:chr11 p15.5
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y83ALLETyCATPAInsulinPhosphoSitePlus
Y116GKFFQyDTWKQIGF2_CPhosphoSitePlus

Dephosphorylation site
IGF2_HUMAN do not have dephosphorylation site.

Mutation site
IGF2_HUMAN do not have mutation site.

Differential expressed protein
IGF2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
IGF2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
IGF2_HUMANINSR_HUMANligand -> receptorHPMR
IGF2_HUMANMPRI_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
IGF2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007275multicellular organismal developmentTASbiological_process
GO:0001503ossificationIEAbiological_process
GO:0001501skeletal system developmentTASbiological_process
GO:0008284positive regulation of cell proliferationICbiological_process
GO:0051897positive regulation of protein kinase B signaling IDAbiological_process
GO:0006006glucose metabolic processIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0042104positive regulation of activated T cell proliferatIDAbiological_process
GO:0050731positive regulation of peptidyl-tyrosine phosphoryISSbiological_process
GO:0006349regulation of gene expression by genetic imprintinTASbiological_process
GO:0005158insulin receptor bindingIPImolecular_function
GO:0008286insulin receptor signaling pathwayTASbiological_process
GO:0006355regulation of transcription, DNA-dependentNASbiological_process
GO:0043085positive regulation of catalytic activityISSbiological_process
GO:0030546receptor activator activityISSmolecular_function
GO:0005179hormone activityIEAmolecular_function
GO:0043539protein serine/threonine kinase activator activityISSmolecular_function
GO:0043410positive regulation of MAPK cascadeIDAbiological_process
GO:0005159insulin-like growth factor receptor bindingTASmolecular_function
GO:0005576extracellular regionTAScellular_component
GO:0051781positive regulation of cell divisionIEAbiological_process
GO:0045840positive regulation of mitosisIDAbiological_process
GO:2000467positive regulation of glycogen (starch) synthase ISSbiological_process
GO:0005515protein bindingIPImolecular_function
GO:2000273positive regulation of receptor activityISSbiological_process
GO:0046628positive regulation of insulin receptor signaling IDAbiological_process
GO:0038028insulin receptor signaling pathway via phosphatidyISSbiological_process
GO:0071902positive regulation of protein serine/threonine kiISSbiological_process
GO:0045725positive regulation of glycogen biosynthetic proceISSbiological_process
GO:0008083growth factor activityIDAmolecular_function
GO:0001934positive regulation of protein phosphorylationISSbiological_process


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