Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ICOS_HUMAN
Description:inducible T-cell co-stimulator [Source:HGNC Symbol;Acc:5351]
Location:chr2 q33.2
Node attribute:PPI(target); PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y180DPNGEyMFMRAPhosphoSitePlus

Dephosphorylation site
ICOS_HUMAN do not have dephosphorylation site.

Mutation site
ICOS_HUMAN do not have mutation site.

Differential expressed protein
ICOS_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ICOS_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ICOSL_HUMANICOS_HUMANotherKEGG
ICOS_HUMANPI3R5_HUMANotherKEGG
ICOS_HUMANCD40L_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04672Intestinal immune network for IgA production
hsa04514Cell adhesion molecules (CAMs)
hsa04660T cell receptor signaling pathway
hsa05340Primary immunodeficiency

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0009897external side of plasma membraneIEAcellular_component
GO:0005886plasma membraneTAScellular_component
GO:0002517T cell tolerance inductionIEAbiological_process
GO:0005887integral to plasma membraneIEAcellular_component
GO:0016337cell-cell adhesionIEAbiological_process
GO:0006955immune responseNASbiological_process
GO:0016021integral to membraneNAScellular_component
GO:0031295T cell costimulationIEAbiological_process
GO:0031295T cell costimulationTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0005576extracellular regionIEAcellular_component


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