| UniProt/SwissProt ID: | I22R2_HUMAN |
| Description: | interleukin 22 receptor, alpha 2 [Source:HGNC Symbol;Acc:14901] |
| Location: | chr6 q23.3 |
| Node attribute: | kinase; receptor; PPI(target) |
| Phosphorylation site |
| I22R2_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| I22R2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| I22R2_HUMAN do not have mutation site. |
| Differential expressed protein |
| I22R2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| I22R2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| IL22_HUMAN | I22R2_HUMAN | ligand -> receptor | HPMR |
| I22R2_HUMAN | JAK1_HUMAN | kinase -> substrate | KEGG |
| PTN6_HUMAN | I22R2_HUMAN | other | KEGG |
| IL22_HUMAN | I22R2_HUMAN | other | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04630 | Jak-STAT signaling pathway |
| hsa04060 | Cytokine-cytokine receptor interaction |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0042516 | regulation of tyrosine phosphorylation of Stat3 pr | IEA | biological_process |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0042516 | regulation of tyrosine phosphorylation of Stat3 pr | ISS | biological_process |
| GO:0042017 | interleukin-22 binding | IDA | molecular_function |
| GO:0005615 | extracellular space | NAS | cellular_component |
| GO:0005829 | cytosol | IEA | cellular_component |
| GO:0042018 | interleukin-22 receptor activity | IDA | molecular_function |