| UniProt/SwissProt ID: | H2B1J_HUMAN |
| Description: | histone cluster 1, H2bj [Source:HGNC Symbol;Acc:4761] |
| Location: | chr6 p22.1 |
| Node attribute: | substrate; gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| T89 | YNKRStITSRE | PhosphoSitePlus | |
| S65 | MGIMNsFVNDI | PhosphoSitePlus | |
| S124 | VTKYTsAK___ | PhosphoSitePlus | |
| Y41 | ESYSIyVYKVL | PhosphoSitePlus | |
| S37 | RSRKEsYSIYV | PhosphoSitePlus | |
| Y38 | SRKESySIYVY | PhosphoSitePlus | |
| Y43 | YSIYVyKVLKQ | PhosphoSitePlus | |
| S88 | HYNKRsTITSR | PhosphoSitePlus | |
| S113 | AKHAVsEGTKA | PhosphoSitePlus | |
| Y84 | SRLAHyNKRST | PhosphoSitePlus | |
| S15 | APKKGsKKAVT | MST1(STK4 | RegPhos |
| Dephosphorylation site |
| H2B1J_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000342886 | K17E | COSMIC | Ovarian Cancer | 21720365 | ENSP00000342886 | K28* | BIOMART | Pancreatic Cancer | 21930507, 21930502 | ENSP00000342886 | P51A | COSMIC | Head and Neck Cancer | 21798893 |
| Differential expressed protein |
| H2B1J_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| H2B1J_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| STK4_HUMAN | H2B1J_HUMAN | kinase -> substrate | RegPhos |
| PO2F1_HUMAN | H2B1J_HUMAN | TF -> target gene | TRANSFAC |
| PO2F2_HUMAN | H2B1J_HUMAN | TF -> target gene | TRANSFAC |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa05322 | Systemic lupus erythematosus |
| hsa05034 | Alcoholism |
| hsa05203 | Viral carcinogenesis |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0046982 | protein heterodimerization activity | IEA | molecular_function |
| GO:0042742 | defense response to bacterium | IEA | biological_process |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0003677 | DNA binding | NAS | molecular_function |
| GO:0000786 | nucleosome | NAS | cellular_component |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0006334 | nucleosome assembly | NAS | biological_process |
| GO:0043565 | sequence-specific DNA binding | IEA | molecular_function |