Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:GLYAT_HUMAN
Description:glycine-N-acyltransferase [Source:HGNC Symbol;Acc:13734]
Location:chr11 q12.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T278QKMSYtLQHVPGly_acyl_tr_CPhosphoSitePlus
Y248VTYVIySHAQKGly_acyl_tr_CPhosphoSitePlus

Dephosphorylation site
GLYAT_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000431688H264DBIOMARTBreast Cancer21930507, 21930502
ENSP00000340200H264DBIOMARTBreast Cancer21930507, 21930502

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000340200Renal CancerNormal vs. CancertissueDown19164279

Hyperphosphorylation site
GLYAT_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ABL1_HUMANGLYAT_HUMANkinase -> substrateRegPhos
ZAGL2_HUMANGLYAT_HUMANkinase -> substrateRegPhos
ABL2_HUMANGLYAT_HUMANkinase -> substrateRegPhos; Robert H Newman (2013)
M4K5_HUMANGLYAT_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa00360Phenylalanine metabolism

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0016746transferase activity, transferring acyl groupsTASmolecular_function
GO:0006544glycine metabolic processISSbiological_process
GO:0006805xenobiotic metabolic processTASbiological_process
GO:0044281small molecule metabolic processTASbiological_process
GO:0009636response to toxinIEAbiological_process
GO:0032787monocarboxylic acid metabolic processISSbiological_process
GO:0005739mitochondrionIEAcellular_component
GO:0006637acyl-CoA metabolic processTASbiological_process
GO:0047961glycine N-acyltransferase activityIEAmolecular_function
GO:0005759mitochondrial matrixTAScellular_component
GO:0047962glycine N-benzoyltransferase activityISSmolecular_function
GO:0005739mitochondrionISScellular_component


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