| UniProt/SwissProt ID: | EXOS5_HUMAN |
| Description: | exosome component 5 [Source:HGNC Symbol;Acc:24662] |
| Location: | chr19 q13.2 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S20 | NGTGSsPRGPG | PhosphoSitePlus; HPRD; phosphoELM; SysPTM | |
| Dephosphorylation site |
| EXOS5_HUMAN do not have dephosphorylation site. |
| Mutation site |
| EXOS5_HUMAN do not have mutation site. |
| Differential expressed protein |
| Ensembl ID | Cancer name | Design | Sample | Change | Ratio | Pubmed |
|---|---|---|---|---|---|---|
| ENSP00000221233 | Gastric Cancer | Metastasis | cell line | Up | 1.4 | 17022644 | ENSP00000221233 | Gastric Cancer | Metastasis | cell line | Up | 1.4 | 17022644 |
| Hyperphosphorylation site |
| EXOS5_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| FGFR1_HUMAN | EXOS5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| KPCA_HUMAN | EXOS5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| MAPK5_HUMAN | EXOS5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CDK4_HUMAN | EXOS5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| PKN1_HUMAN | EXOS5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| MP2K7_HUMAN | EXOS5_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| EXOS5_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005730 | nucleolus | NAS | cellular_component |
| GO:0051607 | defense response to virus | IMP | biological_process |
| GO:0045006 | DNA deamination | IDA | biological_process |
| GO:0000288 | nuclear-transcribed mRNA catabolic process, deaden | TAS | biological_process |
| GO:0003723 | RNA binding | IEA | molecular_function |
| GO:0005737 | cytoplasm | NAS | cellular_component |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0016070 | RNA metabolic process | TAS | biological_process |
| GO:0000178 | exosome (RNase complex) | IDA | cellular_component |
| GO:0000175 | 3'-5'-exoribonuclease activity | NAS | molecular_function |
| GO:0043928 | exonucleolytic nuclear-transcribed mRNA catabolic | IMP | biological_process |
| GO:0005515 | protein binding | IPI | molecular_function |
| GO:0035327 | transcriptionally active chromatin | IMP | cellular_component |
| GO:0006401 | RNA catabolic process | IEA | biological_process |
| GO:0016071 | mRNA metabolic process | TAS | biological_process |
| GO:0010467 | gene expression | TAS | biological_process |
| GO:0006364 | rRNA processing | NAS | biological_process |