Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:EXOS5_HUMAN
Description:exosome component 5 [Source:HGNC Symbol;Acc:24662]
Location:chr19 q13.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S20NGTGSsPRGPGPhosphoSitePlus; HPRD; phosphoELM; SysPTM

Dephosphorylation site
EXOS5_HUMAN do not have dephosphorylation site.

Mutation site
EXOS5_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000221233Gastric CancerMetastasiscell lineUp1.417022644
ENSP00000221233Gastric CancerMetastasiscell lineUp1.417022644

Hyperphosphorylation site
EXOS5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
FGFR1_HUMANEXOS5_HUMANkinase -> substrateRobert H Newman (2013)
KPCA_HUMANEXOS5_HUMANkinase -> substrateRobert H Newman (2013)
MAPK5_HUMANEXOS5_HUMANkinase -> substrateRobert H Newman (2013)
CDK4_HUMANEXOS5_HUMANkinase -> substrateRobert H Newman (2013)
PKN1_HUMANEXOS5_HUMANkinase -> substrateRobert H Newman (2013)
MP2K7_HUMANEXOS5_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
EXOS5_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005730nucleolusNAScellular_component
GO:0051607defense response to virusIMPbiological_process
GO:0045006DNA deaminationIDAbiological_process
GO:0000288nuclear-transcribed mRNA catabolic process, deadenTASbiological_process
GO:0003723RNA bindingIEAmolecular_function
GO:0005737cytoplasmNAScellular_component
GO:0005829cytosolTAScellular_component
GO:0016070RNA metabolic processTASbiological_process
GO:0000178exosome (RNase complex)IDAcellular_component
GO:00001753'-5'-exoribonuclease activityNASmolecular_function
GO:0043928exonucleolytic nuclear-transcribed mRNA catabolic IMPbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0035327transcriptionally active chromatinIMPcellular_component
GO:0006401RNA catabolic processIEAbiological_process
GO:0016071mRNA metabolic processTASbiological_process
GO:0010467gene expressionTASbiological_process
GO:0006364rRNA processingNASbiological_process


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