Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:ELF1_HUMAN
Description:E74-like factor 1 (ets domain transcription factor) [Source:HGNC Symbol;Acc:3316]
Location:chr13 q14.11
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S168SPGASsPEQPKPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S187PPRPDsPATTPPhosphoSitePlus
Y160QVQEKyADSPGPhosphoSitePlus; HPRD
S167DSPGAsSPEQPPhosphoSitePlus; HPRD
S195TTPNIsVKKKNPhosphoSitePlus
S110LLNMDsPGPMLHPRD
S163EKYADsPGASSPhosphoSitePlus; HPRD; phosphoELM
S110LLNMDsPGPMLElf-1_NPhosphoSitePlus
T191DSPATtPNISVPhosphoSitePlus
T559TSVIKtQETKTPhosphoSitePlus
T231KYIKWtQREKGEtsPhosphoSitePlus
S376VQPTQsPYPTQPhosphoSitePlus
S333RSRVSsSPGVKPhosphoSitePlus
S334SRVSSsPGVKGPhosphoSitePlus
S432VPVVVsPRNQQPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S332SRSRVsSSPGVPhosphoSitePlus
S474QAIPSsQPMTVPhosphoSitePlus; HPRD; phosphoELM
Y261KPDMNyETMGREtsPhosphoSitePlus
T190PDSPAtTPNISPhosphoSitePlus
T566ETKTLtQEVEKPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
ELF1_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000239882P28SBIOMARTBreast Cancer21930507, 21930502
ENSP00000239882P225ACOSMICOvarian Cancer21720365
ENSP00000239882L51VCOSMICHead and Neck Cancer21798893
ENSP00000239882S604CCOSMICHead and Neck Cancer21798893
ENSP00000239882*620YCOSMICIntestines Cancer16959974

Differential expressed protein
ELF1_HUMAN is not differential expressed protein.

Hyperphosphorylation site
ELF1_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
ELF1_HUMANNFKB1_HUMANTF -> target geneTRANSFAC
ELF1_HUMANIL2RA_HUMANTF -> target geneTRANSFAC
ELF1_HUMANIL2_HUMANTF -> target geneTRANSFAC
ELF1_HUMANCD3Z_HUMANTF -> target geneTRANSFAC
ELF1_HUMANLYN_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
ELF1_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006351transcription, DNA-dependentIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0001817regulation of cytokine productionIEAbiological_process
GO:0050860negative regulation of T cell receptor signaling pIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenNASbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0003700sequence-specific DNA binding transcription factorIDAmolecular_function


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