Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:EFNA5_HUMAN
Description:ephrin-A5 [Source:HGNC Symbol;Acc:3225]
Location:chr5 q21.3
Node attribute:ligand

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T8HVEMLtLVFLVPhosphoSitePlus

Dephosphorylation site
EFNA5_HUMAN do not have dephosphorylation site.

Mutation site
EFNA5_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000328777Prostate CancerTreatment (androgen-starved vs. androgen-stimulated)cell lineUp214729644

Hyperphosphorylation site
EFNA5_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
EFNA5_HUMANEPHA4_HUMANligand -> receptorHPMR
EFNA5_HUMANEPHA2_HUMANligand -> receptorHPMR
EFNA5_HUMANEPHA8_HUMANligand -> receptorHPMR
EFNA5_HUMANEPHA5_HUMANligand -> receptorHPMR
EFNA5_HUMANEPHA6_HUMANligand -> receptorHPMR
EFNA5_HUMANEPHA3_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04360Axon guidance

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0032319regulation of Rho GTPase activityIDAbiological_process
GO:0050919negative chemotaxisIEAbiological_process
GO:0022407regulation of cell-cell adhesionIDAbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0032314regulation of Rac GTPase activityISSbiological_process
GO:0048013ephrin receptor signaling pathwayIDAbiological_process
GO:0005886plasma membraneISScellular_component
GO:0007399nervous system developmentTASbiological_process
GO:0031362anchored to external side of plasma membraneIDAcellular_component
GO:0007411axon guidanceIEAbiological_process
GO:0061178regulation of insulin secretion involved in cellulIEAbiological_process
GO:0048013ephrin receptor signaling pathwayIEAbiological_process
GO:0032956regulation of actin cytoskeleton organizationIEAbiological_process
GO:0032956regulation of actin cytoskeleton organizationIDAbiological_process
GO:0050731positive regulation of peptidyl-tyrosine phosphoryIEAbiological_process
GO:0005901caveolaIEAcellular_component
GO:0050731positive regulation of peptidyl-tyrosine phosphoryISSbiological_process
GO:0045499chemorepellent activityIEAmolecular_function
GO:0070507regulation of microtubule cytoskeleton organizatioIDAbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0046875ephrin receptor bindingIPImolecular_function
GO:0032314regulation of Rac GTPase activityIEAbiological_process
GO:0061178regulation of insulin secretion involved in cellulISSbiological_process
GO:0046875ephrin receptor bindingIEAmolecular_function
GO:0022407regulation of cell-cell adhesionIEAbiological_process
GO:0016020membraneIEAcellular_component
GO:0051893regulation of focal adhesion assemblyIDAbiological_process
GO:0031290retinal ganglion cell axon guidanceIEAbiological_process


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