| UniProt/SwissProt ID: | EFNA2_HUMAN |
| Description: | ephrin-A2 [Source:HGNC Symbol;Acc:3222] |
| Location: | chr19 p13.3 |
| Node attribute: | ligand |
| Phosphorylation site |
| EFNA2_HUMAN do not have phosphorylation site. |
| Dephosphorylation site |
| EFNA2_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000215368 | *214Y | COSMIC | Ovarian Cancer | 21720365 | ENSP00000215368 | *214C | COSMIC | Neoplasms by Histologic Type | 12673678 |
| Differential expressed protein |
| EFNA2_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| EFNA2_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| EFNA2_HUMAN | EPHA3_HUMAN | ligand -> receptor | HPMR |
| EFNA2_HUMAN | EPHA5_HUMAN | ligand -> receptor | HPMR |
| EFNA2_HUMAN | EPHA6_HUMAN | ligand -> receptor | HPMR |
| EFNA2_HUMAN | EPHA4_HUMAN | ligand -> receptor | HPMR |
| EFNA2_HUMAN | EPHA8_HUMAN | ligand -> receptor | HPMR |
| EFNA2_HUMAN | EPHA7_HUMAN | ligand -> receptor | HPMR |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04360 | Axon guidance |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0046849 | bone remodeling | IEA | biological_process |
| GO:0031225 | anchored to membrane | IEA | cellular_component |
| GO:0030316 | osteoclast differentiation | ISS | biological_process |
| GO:0007267 | cell-cell signaling | TAS | biological_process |
| GO:0016020 | membrane | IEA | cellular_component |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0046875 | ephrin receptor binding | IEA | molecular_function |
| GO:0048013 | ephrin receptor signaling pathway | ISS | biological_process |
| GO:0030316 | osteoclast differentiation | IEA | biological_process |
| GO:0046849 | bone remodeling | ISS | biological_process |
| GO:0048013 | ephrin receptor signaling pathway | IEA | biological_process |