Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DX39A_HUMAN
Description:DEAD (Asp-Glu-Ala-Asp) box polypeptide 39A [Source:HGNC Symbol;Acc:17821]
Location:chr19 p13.12
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S183LVRNRsFSLKNDEADPhosphoSitePlus
T171HVVVGtPGRILHPRD; phosphoELM
S40KGSYVsIHSSGPhosphoSitePlus; HPRD; phosphoELM
S37KDIKGsYVSIHPhosphoSitePlus; HPRD
T171HVVVGtPGRILDEADPhosphoSitePlus
Y265GLQQYyVKLKDPhosphoSitePlus
T382AGRFGtKGLAIPhosphoSitePlus
Y13NDLLDyDEEEEPhosphoSitePlus
S43YVSIHsSGFRDPhosphoSitePlus
S145PSVKVsVFFGGDEADPhosphoSitePlus
S25QAPQEsTPAPPHPRD
S426TYIEQsR____PhosphoSitePlus
S426TYIEQHPRD
Y38DIKGSyVSIHSPhosphoSitePlus

Dephosphorylation site
DX39A_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000242776R134HBIOMARTPancreatic Cancer21930507, 21930502
ENSP00000242776R174HCOSMICOvarian Cancer21720365

Differential expressed protein
DX39A_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DX39A_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NEK4_HUMANDX39A_HUMANkinase -> substrateRobert H Newman (2013)
ST17A_HUMANDX39A_HUMANkinase -> substrateRobert H Newman (2013)
WEE1_HUMANDX39A_HUMANkinase -> substrateRobert H Newman (2013)
CLK2_HUMANDX39A_HUMANkinase -> substrateRobert H Newman (2013)
CDKL5_HUMANDX39A_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
DX39A_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0004386helicase activityIEAmolecular_function
GO:0008026ATP-dependent helicase activityIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0005634nucleusIDAcellular_component
GO:0006406mRNA export from nucleusIGIbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0000398mRNA splicing, via spliceosomeIGIbiological_process
GO:0005524ATP bindingIEAmolecular_function


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