Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:DNM1L_HUMAN
Description:dynamin 1-like [Source:HGNC Symbol;Acc:2973]
Location:chr12 p11.21
Node attribute:effector

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S607LAEEKsKPIPIPhosphoSitePlus; HPRD; phosphoELM
T193NTDMAtSEALKDynamin_NPhosphoSitePlus
S579PIMPAsPQKGHHPRD
S616PIMPAsPQKGHPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S529LPSAVsRDKSSPhosphoSitePlus; HPRD
S179ISNPNsIILAVDynamin_NPhosphoSitePlus
T78EDKRKtTGEENDynamin_NPhosphoSitePlus
S684KDTLQsELVGQHPRD
S658KDTLQsELVGQHPRD
S570LAEEKsKPIPIHPRD
S581LAEEKsKPIPIHPRD
T400AIRNAtGPRPADynamin_MPhosphoSitePlus
S637VARKLsAREQRPKA_groupphosphoELM
S590PIMPAsPQKGHHPRD
S647KDTLQsELVGQHPRD
S412FVPEVsFELLVDynamin_MPhosphoSitePlus
T193NTDMAtSEALKHPRD
T79DKRKTtGEENGDynamin_NPhosphoSitePlus
S693GQLYKsSLLDDPhosphoSitePlus
S548ASQEPsPAASAPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S194TDMATsEALKIHPRD
S637VARKLsAREQRPhosphoSitePlus
T586VQEPTtGNWRGPhosphoSitePlus

Dephosphorylation site
DNM1L_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000266481M439ITCGAOvarian Cancer21720365, 18772890

Differential expressed protein
DNM1L_HUMAN is not differential expressed protein.

Hyperphosphorylation site
DNM1L_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
GBG10_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBB1_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBG5_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBG8_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBG11_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBB5_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBG1_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBG3_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBB2_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBG2_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBG12_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBB3_HUMANDNM1L_HUMANGprotein -> effectorgpDB
GBG13_HUMANDNM1L_HUMANGprotein -> effectorgpDB

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04666Fc gamma R-mediated phagocytosis
hsa04961Endocrine and other factor-regulated calcium reabs
hsa05100Bacterial invasion of epithelial cells
hsa04721Synaptic vesicle cycle
hsa04144Endocytosis

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005515protein bindingIEAmolecular_function
GO:0006921cellular component disassembly involved in executiTASbiological_process
GO:0048471perinuclear region of cytoplasmIDAcellular_component
GO:0090149membrane fission involved in mitochondrial fissionIDAbiological_process
GO:0005777peroxisomeIDAcellular_component
GO:0043653mitochondrial fragmentation involved in apoptotic IMPbiological_process
GO:1900063regulation of peroxisome organizationIMPbiological_process
GO:0051289protein homotetramerizationIDAbiological_process
GO:0005741mitochondrial outer membraneIEAcellular_component
GO:0006915apoptotic processTASbiological_process
GO:0005737cytoplasmIDAcellular_component
GO:0003374dynamin polymerization involved in mitochondrial fIDAbiological_process
GO:0031625ubiquitin protein ligase bindingIPImolecular_function
GO:0005525GTP bindingIEAmolecular_function
GO:0005829cytosolTAScellular_component
GO:0012505endomembrane systemIEAcellular_component
GO:0090200positive regulation of release of cytochrome c froIMPbiological_process
GO:0050714positive regulation of protein secretionIDAbiological_process
GO:0003924GTPase activityIEAmolecular_function
GO:0070584mitochondrion morphogenesisIMPbiological_process
GO:2001244positive regulation of intrinsic apoptotic signaliIMPbiological_process
GO:0005794Golgi apparatusIDAcellular_component
GO:0043234protein complexIDAcellular_component
GO:0090141positive regulation of mitochondrial fissionTASbiological_process
GO:0016559peroxisome fissionIDAbiological_process
GO:0005874microtubuleIDAcellular_component
GO:0010821regulation of mitochondrion organizationIMPbiological_process
GO:0000266mitochondrial fissionIEAbiological_process
GO:0005515protein bindingIPImolecular_function
GO:0005741mitochondrial outer membraneIDAcellular_component
GO:0042802identical protein bindingIPImolecular_function


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