Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CSTFT_HUMAN
Description:cleavage stimulation factor, 3' pre-RNA, subunit 2, 64kDa, tau variant [Source:HGNC Symbol;Acc:17086]
Location:chr10 q21.1
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S601PEQRQsILILKPhosphoSitePlus
S113APIIDsPYGDPPhosphoSitePlus
T320PRGPVtPGGLPPhosphoSitePlus
S563QPSSFsPGQSQPhosphoSitePlus; HPRD; phosphoELM; SysPTM
S561GSQPSsFSPGQPhosphoSitePlus; HPRD
S567FSPGQsQVTPQPhosphoSitePlus; HPRD; phosphoELM
T198RKIHVtPLIPGPhosphoSitePlus
S205LIPGKsQSVSVPhosphoSitePlus
S557SKQGGsQPSSFPhosphoSitePlus; HPRD; phosphoELM

Dephosphorylation site
CSTFT_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000332444M140ICOSMICOvarian Cancer21720365
ENSP00000332444V151FCOSMICHead and Neck Cancer21798893
ENSP00000332444G545EBIOMARTBreast Cancer21930507, 21930502
ENSP00000332444G502WCOSMICHead and Neck Cancer21798893

Differential expressed protein
CSTFT_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CSTFT_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
NEK4_HUMANCSTFT_HUMANkinase -> substrateRobert H Newman (2013)
CDKL5_HUMANCSTFT_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CSTFT_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0006397mRNA processingIEAbiological_process
GO:0005622intracellularIDAcellular_component
GO:0000166nucleotide bindingIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0003723RNA bindingIEAmolecular_function
GO:0003676nucleic acid bindingIEAmolecular_function


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