Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CPZIP_HUMAN
Description:RCSD domain containing 1 [Source:HGNC Symbol;Acc:28310]
Location:chr1 q24.2
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S192FRAVEsSQQNGPhosphoSitePlus
S216SKAPGsPLSSEJNK1(MAPK8)(in vitro) RegPhos
S193RAVESsQQNGAPhosphoSitePlus
S73SPPNAsHPPKFPhosphoSitePlus; HPRD
S267EKARRsSEEVDHPRD
S171KRRPPsRRFRRPhosphoSitePlus
S83FKVKSsPLIEKJNK1(MAPK8)(in vitro) RegPhos
S82KFKVKsSPLIEPhosphoSitePlus
S135VRSRPsEAEEVPhosphoSitePlus
S116LKAMVsPFHSPPhosphoSitePlus; HPRD
Y156SHLPCyNKVRTPhosphoSitePlus
S132SPGVRsRPSEAPhosphoSitePlus
S244LRRSPsRTEKQRCSDPhosphoSitePlus
S17VDNSAsPSVAQPhosphoSitePlus
S151QPPEGsHLPCYPhosphoSitePlus
S108GASPKsPGLKAPhosphoSitePlus
S268KARRSsEEVDGRCSDPhosphoSitePlus
T124HSPPStPSSPGPhosphoSitePlus; HPRD
S267EKARRsSEEVDRCSDPhosphoSitePlus
S126PPSTPsSPGVRPhosphoSitePlus
S219PGSPLsSEGAAPhosphoSitePlus
S177RRFRRsQSDCGPhosphoSitePlus; HPRD
S179FRRSQsDCGELPhosphoSitePlus; HPRD
S268KARRSsEEVDGHPRD
S68NGEEKsPPNASPhosphoSitePlus; HPRD
S220GSPLSsEGAAGPhosphoSitePlus
S105LLPGAsPKSPGPhosphoSitePlus
S68NGEEKsPPNASJNK1(MAPK8)(in vitro) RegPhos
S123FHSPPsTPSSPPhosphoSitePlus; HPRD
S108GASPKsPGLKAp38g(MAPK12RegPhos
S216SKAPGsPLSSEPhosphoSitePlus; HPRD
T287PESPQtSGPEARCSDPhosphoSitePlus
S298ENRCGsPREEKRCSDPhosphoSitePlus
S242PPLRRsPSRTERCSDPhosphoSitePlus
S244LRRSPsRTEKQMAPKAPK2RegPhos
S244LRRSPsRTEKQMAPKAPK3RegPhos
S127PSTPSsPGVRSPhosphoSitePlus; HPRD
S164VRTRGsIKRRPPhosphoSitePlus
S351KETPHsPPGGVPhosphoSitePlus; HPRD
S284EEVPEsPQTSGRCSDPhosphoSitePlus
S108GASPKsPGLKAp38d(MAPK13RegPhos
S120VSPFHsPPSTPPhosphoSitePlus; HPRD
S179FRRSQsDCGELMAPKAPK2RegPhos
S179FRRSQsDCGELMAPKAPK3RegPhos
S83FKVKSsPLIEKPhosphoSitePlus
T94LQANLtFDPAAPhosphoSitePlus

Dephosphorylation site
CPZIP_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000356828S333NCOSMICCentral Nervous System Neoplasms18772890
ENSP00000356828S333NTCGANeoplasms by Histologic Type21720365, 18772890
ENSP00000356828S219FTCGANeoplasms by Histologic Type21720365, 18772890
ENSP00000356828K263NCOSMICOvarian Cancer21720365
ENSP00000356828K263NTCGAOvarian Cancer21720365, 18772890
ENSP00000356828S219FCOSMICCentral Nervous System Neoplasms18772890
ENSP00000356828I86FTCGA, COSMICOvarian Cancer21720365, 18772890

Differential expressed protein
CPZIP_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CPZIP_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
MK08_HUMANCPZIP_HUMANkinase -> substrateRegPhos
MAPK2_HUMANCPZIP_HUMANkinase -> substrateRegPhos
MAPK3_HUMANCPZIP_HUMANkinase -> substrateRegPhos

Function Annotation
KEGG Pathway
CPZIP_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0051015actin filament bindingIPImolecular_function
GO:0005884actin filamentICcellular_component
GO:0003009skeletal muscle contractionISSbiological_process
GO:0071474cellular hyperosmotic responseIDAbiological_process


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