| UniProt/SwissProt ID: | CPT1C_HUMAN |
| Description: | carnitine palmitoyltransferase 1C [Source:HGNC Symbol;Acc:18540] |
| Location: | chr19 q13.33 |
| Node attribute: | PPI(source); PPI(target); gene |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S538 | GAKILsENVDC | Carn_acyltransf | PhosphoSitePlus |
| Dephosphorylation site |
| CPT1C_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000384465 | S694* | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000319343 | S705* | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000384465 | T595A | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000319343 | S244F | COSMIC | Skin Cancer | 21984974 | ENSP00000319343 | T606A | COSMIC | Ovarian Cancer | 21720365 | ENSP00000376303 | S705* | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000319343 | R652H | COSMIC | Head and Neck Cancer | 21984974 |
| Differential expressed protein |
| CPT1C_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CPT1C_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| ACACB_HUMAN | CPT1C_HUMAN | other | KEGG |
| CPT1C_HUMAN | ACSL1_HUMAN | other | KEGG |
| STAT3_HUMAN | CPT1C_HUMAN | TF -> target gene | KEGG |
| PPARA_HUMAN | CPT1C_HUMAN | TF -> target gene | KEGG |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa00071 | Fatty acid metabolism |
| hsa04920 | Adipocytokine signaling pathway |
| hsa03320 | PPAR signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005741 | mitochondrial outer membrane | IEA | cellular_component |
| GO:0016021 | integral to membrane | IEA | cellular_component |
| GO:0030054 | cell junction | IEA | cellular_component |
| GO:0006635 | fatty acid beta-oxidation | IEA | biological_process |
| GO:0045202 | synapse | IEA | cellular_component |
| GO:0004095 | carnitine O-palmitoyltransferase activity | IEA | molecular_function |
| GO:0016746 | transferase activity, transferring acyl groups | IEA | molecular_function |
| GO:0005739 | mitochondrion | IEA | cellular_component |