Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:COT2_HUMAN
Description:nuclear receptor subfamily 2, group F, member 2 [Source:HGNC Symbol;Acc:7976]
Location:chr15 q26.2
Node attribute:TF

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y348CALEEyVRSQYHormone_recepPhosphoSitePlus

Dephosphorylation site
COT2_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000377721L365PCOSMICOvarian Cancer20826764
ENSP00000377721R109WCOSMICOvarian Cancer21720365

Differential expressed protein
COT2_HUMAN is not differential expressed protein.

Hyperphosphorylation site
COT2_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
COT2_HUMANAPOA1_HUMANTF -> target geneTRANSFAC
COT2_HUMANHBG1_HUMANTF -> target geneTRANSFAC
COT2_HUMANAPOB_HUMANTF -> target geneTRANSFAC
COT2_HUMANAPOC3_HUMANTF -> target geneTRANSFAC
COT2_HUMANFA9_HUMANTF -> target geneTRANSFAC
COT2_HUMANHBE_HUMANTF -> target geneTRANSFAC
COT2_HUMANHNF4A_HUMANTF -> target geneTRANSFAC
COT2_HUMANAACS_HUMANTF -> target geneTRANSFAC
COT2_HUMANAPOA4_HUMANTF -> target geneTRANSFAC

Function Annotation
KEGG Pathway
COT2_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0009956radial pattern formationIEAbiological_process
GO:0030900forebrain developmentIEAbiological_process
GO:0043565sequence-specific DNA bindingIEAmolecular_function
GO:0009566fertilizationIEAbiological_process
GO:0006355regulation of transcription, DNA-dependentIEAbiological_process
GO:0003707steroid hormone receptor activityIEAmolecular_function
GO:0003714transcription corepressor activityTASmolecular_function
GO:0006629lipid metabolic processTASbiological_process
GO:0042803protein homodimerization activityIPImolecular_function
GO:0045736negative regulation of cyclin-dependent protein kiIDAbiological_process
GO:0006357regulation of transcription from RNA polymerase IIIEAbiological_process
GO:0000122negative regulation of transcription from RNA polyIEAbiological_process
GO:0005634nucleusIEAcellular_component
GO:0001701in utero embryonic developmentIEAbiological_process
GO:0004879ligand-activated sequence-specific DNA binding RNAIEAmolecular_function
GO:0008270zinc ion bindingIEAmolecular_function
GO:0060674placenta blood vessel developmentIEAbiological_process
GO:0045892negative regulation of transcription, DNA-dependenIDAbiological_process
GO:0001937negative regulation of endothelial cell proliferatIMPbiological_process
GO:0001972retinoic acid bindingIDAmolecular_function
GO:0010596negative regulation of endothelial cell migrationIMPbiological_process
GO:0030522intracellular receptor mediated signaling pathwayIDAbiological_process
GO:0060173limb developmentIEAbiological_process
GO:0001764neuron migrationIEAbiological_process
GO:0045893positive regulation of transcription, DNA-dependenIDAbiological_process
GO:0007519skeletal muscle tissue developmentIEAbiological_process
GO:0032355response to estradiol stimulusIEAbiological_process
GO:0009952anterior/posterior pattern specificationIEAbiological_process
GO:0001945lymph vessel developmentIEAbiological_process
GO:0060707trophoblast giant cell differentiationIEAbiological_process
GO:0048514blood vessel morphogenesisIEAbiological_process
GO:0043401steroid hormone mediated signaling pathwayIEAbiological_process
GO:0001893maternal placenta developmentIEAbiological_process
GO:0006357regulation of transcription from RNA polymerase IITASbiological_process
GO:0007165signal transductionTASbiological_process
GO:0003700sequence-specific DNA binding transcription factorICmolecular_function
GO:0003677DNA bindingIEAmolecular_function
GO:0005515protein bindingIPImolecular_function
GO:0060849regulation of transcription involved in lymphatic IMPbiological_process