Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:COLI_HUMAN
Description:proopiomelanocortin [Source:HGNC Symbol;Acc:9201]
Location:chr2 p23.3
Node attribute:ligand; PPI(target)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
S108KREDVsAGEDCPhosphoSitePlus
S97SSSSGsSGAGQPhosphoSitePlus
S95RNSSSsGSSGAPhosphoSitePlus
S168GAEDEsAEAFPACTH_domainPhosphoSitePlus

Dephosphorylation site
COLI_HUMAN do not have dephosphorylation site.

Mutation site
COLI_HUMAN do not have mutation site.

Differential expressed protein
COLI_HUMAN is not differential expressed protein.

Hyperphosphorylation site
COLI_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
COLI_HUMANMC5R_HUMANligand -> receptorHPMR
COLI_HUMANACTHR_HUMANligand -> receptorHPMR
COLI_HUMANMC3R_HUMANligand -> receptorHPMR
COLI_HUMANMSHR_HUMANligand -> receptorHPMR
COLI_HUMANOPRM_HUMANligand -> receptorHPMR
COLI_HUMANOPRK_HUMANligand -> receptorHPMR
STAT3_HUMANCOLI_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04916Melanogenesis
hsa04920Adipocytokine signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0030141secretory granuleIEAcellular_component
GO:0006091generation of precursor metabolites and energyIMPbiological_process
GO:0005576extracellular regionIEAcellular_component
GO:0016486peptide hormone processingTASbiological_process
GO:0007165signal transductionIMPbiological_process
GO:0070996type 1 melanocortin receptor bindingIDAmolecular_function
GO:0005737cytoplasmIEAcellular_component
GO:0031782type 4 melanocortin receptor bindingIPImolecular_function
GO:0034641cellular nitrogen compound metabolic processTASbiological_process
GO:0008217regulation of blood pressureIEAbiological_process
GO:0005615extracellular spaceIDAcellular_component
GO:0007267cell-cell signalingIMPbiological_process
GO:0045944positive regulation of transcription from RNA polyIDAbiological_process
GO:0032098regulation of appetiteIMPbiological_process
GO:0001664G-protein coupled receptor bindingIDAmolecular_function
GO:0005737cytoplasmISScellular_component
GO:0005179hormone activityIEAmolecular_function
GO:0044281small molecule metabolic processTASbiological_process
GO:0032720negative regulation of tumor necrosis factor produIDAbiological_process
GO:0033059cellular pigmentationIMPbiological_process
GO:0007218neuropeptide signaling pathwayIEAbiological_process
GO:0005102receptor bindingIMPmolecular_function
GO:0005782peroxisomal matrixIDAcellular_component
GO:0031781type 3 melanocortin receptor bindingIPImolecular_function


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