Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:MC5R_HUMAN
Description:melanocortin 5 receptor [Source:HGNC Symbol;Acc:6933]
Location:chr18 p11.21
Node attribute:receptor

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T143VDRYVtIFYAL7tm_1PhosphoSitePlus
T155YHHIMtARRSG7tm_1PhosphoSitePlus
Y150FYALRyHHIMT7tm_1PhosphoSitePlus

Dephosphorylation site
MC5R_HUMAN do not have dephosphorylation site.

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000318077V126LBIOMARTBreast Cancer21930507, 21930502
ENSP00000318077T171MCOSMICOvarian Cancer21720365
ENSP00000318077F306IBIOMARTHepatocellular Carcinoma21930507, 21930502
ENSP00000318077K27NCOSMICOvarian Cancer21720365
ENSP00000318077T171MTCGAOvarian Cancer21720365, 18772890
ENSP00000318077I153TCOSMICLung Cancer20668451

Differential expressed protein
MC5R_HUMAN is not differential expressed protein.

Hyperphosphorylation site
MC5R_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
COLI_HUMANMC5R_HUMANligand -> receptorHPMR

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04080Neuroactive ligand-receptor interaction

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0005886plasma membraneTAScellular_component
GO:0042562hormone bindingIEAmolecular_function
GO:0016021integral to membraneIEAcellular_component
GO:0007186G-protein coupled receptor signaling pathwayIEAbiological_process
GO:0007187G-protein coupled receptor signaling pathway, coupTASbiological_process
GO:0030819positive regulation of cAMP biosynthetic processIDAbiological_process
GO:0004930G-protein coupled receptor activityIEAmolecular_function
GO:0005887integral to plasma membraneTAScellular_component
GO:0004977melanocortin receptor activityIEAmolecular_function
GO:0005515protein bindingIPImolecular_function


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