Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CLK4_HUMAN
Description:CDC-like kinase 4 [Source:HGNC Symbol;Acc:13659]
Location:chr5 q35.3
Node attribute:kinase

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y76RYVDEyRNDYCPhosphoSitePlus
S126CSSHQsRSKSHPhosphoSitePlus
S138RKRSRsIEDDEPhosphoSitePlus; HPRD; phosphoELM
T336DEHHStLVSTRPkinasePhosphoSitePlus
S136HRRKRsRSIEDPhosphoSitePlus; HPRD; phosphoELM
T340STLVStRHYRAPkinasePhosphoSitePlus
S335DDEHHsTLVSTPkinasePhosphoSitePlus
Y343VSTRHyRAPEVPkinasePhosphoSitePlus
S339HSTLVsTRHYRHPRD
T340STLVStRHYRAHPRD
Y80EYRNDyCEGYVPhosphoSitePlus
S339HSTLVsTRHYRPkinasePhosphoSitePlus

Dephosphorylation site
CLK4_HUMAN do not have dephosphorylation site.

Mutation site
CLK4_HUMAN do not have mutation site.

Differential expressed protein
CLK4_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CLK4_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CLK4_HUMANZN277_HUMANkinase -> substrateRobert H Newman (2013)
CLK4_HUMANZYX_HUMANkinase -> substrateRobert H Newman (2013)

Function Annotation
KEGG Pathway
CLK4_HUMAN is not in KEGG pathway.

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0046777protein autophosphorylationIEAbiological_process
GO:0016772transferase activity, transferring phosphorus-contIEAmolecular_function
GO:0018108peptidyl-tyrosine phosphorylationIEAbiological_process
GO:0004712protein serine/threonine/tyrosine kinase activityIEAmolecular_function
GO:0043484regulation of RNA splicingIMPbiological_process
GO:0004672protein kinase activityIEAmolecular_function
GO:0005634nucleusIEAcellular_component
GO:0006468protein phosphorylationIEAbiological_process
GO:0005524ATP bindingIEAmolecular_function
GO:0004713protein tyrosine kinase activityIEAmolecular_function
GO:0004674protein serine/threonine kinase activityIEAmolecular_function


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