| UniProt/SwissProt ID: | ZN277_HUMAN |
| Description: | zinc finger protein 277 [Source:HGNC Symbol;Acc:13070] |
| Location: | chr7 q31.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S293 | QEDDWsDWEEH | PhosphoSitePlus | |
| S4 | TQGA | HPRD | |
| Dephosphorylation site |
| ZN277_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000354501 | I332L | HPI | Breast Cancer | 16959974 | ENSP00000354501 | L445F | COSMIC | Breast Cancer | 16959974 | ENSP00000354501 | I332L | COSMIC | Breast Cancer | 16959974 | ENSP00000354501 | F171L | COSMIC | Ovarian Cancer | 21720365 | ENSP00000354501 | R256K | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000354501 | Q130K | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000354501 | R256T | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000354501 | Q130K | COSMIC | Ovarian Cancer | 21720365 | ENSP00000354501 | F171L | TCGA | Ovarian Cancer | 21720365, 18772890 | ENSP00000354501 | L445F | HPI | Breast Cancer | 16959974 |
| Differential expressed protein |
| ZN277_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| ZN277_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CLK4_HUMAN | ZN277_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| ZN277_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005634 | nucleus | NAS | cellular_component |
| GO:0006355 | regulation of transcription, DNA-dependent | NAS | biological_process |
| GO:0006351 | transcription, DNA-dependent | IEA | biological_process |
| GO:0003700 | sequence-specific DNA binding transcription factor | NAS | molecular_function |
| GO:0005622 | intracellular | IEA | cellular_component |
| GO:0003677 | DNA binding | IEA | molecular_function |
| GO:0008270 | zinc ion binding | IEA | molecular_function |