| UniProt/SwissProt ID: | CLK4_HUMAN |
| Description: | CDC-like kinase 4 [Source:HGNC Symbol;Acc:13659] |
| Location: | chr5 q35.3 |
| Node attribute: | kinase |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| Y76 | RYVDEyRNDYC | PhosphoSitePlus | |
| S126 | CSSHQsRSKSH | PhosphoSitePlus | |
| S138 | RKRSRsIEDDE | PhosphoSitePlus; HPRD; phosphoELM | |
| T336 | DEHHStLVSTR | Pkinase | PhosphoSitePlus |
| S136 | HRRKRsRSIED | PhosphoSitePlus; HPRD; phosphoELM | |
| T340 | STLVStRHYRA | Pkinase | PhosphoSitePlus |
| S335 | DDEHHsTLVST | Pkinase | PhosphoSitePlus |
| Y343 | VSTRHyRAPEV | Pkinase | PhosphoSitePlus |
| S339 | HSTLVsTRHYR | HPRD | |
| T340 | STLVStRHYRA | HPRD | |
| Y80 | EYRNDyCEGYV | PhosphoSitePlus | |
| S339 | HSTLVsTRHYR | Pkinase | PhosphoSitePlus |
| Dephosphorylation site |
| CLK4_HUMAN do not have dephosphorylation site. |
| Mutation site |
| CLK4_HUMAN do not have mutation site. |
| Differential expressed protein |
| CLK4_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| CLK4_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| CLK4_HUMAN | ZN277_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| CLK4_HUMAN | ZYX_HUMAN | kinase -> substrate | Robert H Newman (2013) |
| Function Annotation |
| KEGG Pathway |
| CLK4_HUMAN is not in KEGG pathway. |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0046777 | protein autophosphorylation | IEA | biological_process |
| GO:0016772 | transferase activity, transferring phosphorus-cont | IEA | molecular_function |
| GO:0018108 | peptidyl-tyrosine phosphorylation | IEA | biological_process |
| GO:0004712 | protein serine/threonine/tyrosine kinase activity | IEA | molecular_function |
| GO:0043484 | regulation of RNA splicing | IMP | biological_process |
| GO:0004672 | protein kinase activity | IEA | molecular_function |
| GO:0005634 | nucleus | IEA | cellular_component |
| GO:0006468 | protein phosphorylation | IEA | biological_process |
| GO:0005524 | ATP binding | IEA | molecular_function |
| GO:0004713 | protein tyrosine kinase activity | IEA | molecular_function |
| GO:0004674 | protein serine/threonine kinase activity | IEA | molecular_function |