Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CD33_HUMAN
Description:CD33 molecule [Source:HGNC Symbol;Acc:1659]
Location:chr19 q13.41
Node attribute:substrate

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y358DTSTEySEVRTPhosphoSitePlus; RegPhos
S248FPGDGsGKQETDUF998PhosphoSitePlus
Y340DEELHyASLNFSrcRegPhos
Y340DEELHyASLNFSRCHPRD; phosphoELM; RegPhos
Y340DEELHyASLNFLckphosphoELM; RegPhos
T302NDTHPtTGSASPhosphoSitePlus
T239VPQNPtTGIFPDUF998PhosphoSitePlus
Y340DEELHyASLNFPhosphoSitePlus; phosphoELM; RegPhos
T226VTTERtIQLNVPhosphoSitePlus
T363YSEVRtQ____PhosphoSitePlus
Y358DTSTEySEVRphosphoELM

Dephosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
Y340EMDEELHyASLNFHGPTPN6HPRD

Mutation site
Ensembl IDVariationSourceCancer namePubmed
ENSP00000262262M17ICOSMICSkin Cancer21984974
ENSP00000262262P46HBIOMARTBreast Cancer21930507, 21930502
ENSP00000262262Q228HBIOMARTBrain Cancer21930507, 21930502

Differential expressed protein
CD33_HUMAN is not differential expressed protein.

Hyperphosphorylation site
CD33_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
SRC_HUMANCD33_HUMANkinase -> substrateHPRD; RegPhos
LCK_HUMANCD33_HUMANkinase -> substrateRobert H Newman (2013)
ZAGL2_HUMANCD33_HUMANkinase -> substrateRegPhos
PTN6_HUMANCD33_HUMANphosphatase -> substrateHPRD

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa04640Hematopoietic cell lineage

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0007165signal transductionTASbiological_process
GO:0005887integral to plasma membraneTAScellular_component
GO:0005515protein bindingIEAmolecular_function
GO:0007155cell adhesionIEAbiological_process
GO:0004872receptor activityTASmolecular_function
GO:0005886plasma membraneTAScellular_component
GO:0009897external side of plasma membraneIDAcellular_component
GO:0007267cell-cell signalingTASbiological_process
GO:0008285negative regulation of cell proliferationTASbiological_process


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