Protein information
  Protein summary    Phosphorylation site    Dephosphorylation site    Mutation site
  Differential expressed protein    Hyperphosphorylation site    Direct interaction pair    Function Annotation

Protein Summary
UniProt/SwissProt ID:CD14_HUMAN
Description:CD14 molecule [Source:HGNC Symbol;Acc:1628]
Location:chr5 q31.3
Node attribute:PPI(source)

Phosphorylation site
PositionPhosphoPeptideCatalytic kinaseSource
T95RVRRLtVGAAQPhosphoSitePlus

Dephosphorylation site
CD14_HUMAN do not have dephosphorylation site.

Mutation site
CD14_HUMAN do not have mutation site.

Differential expressed protein
Ensembl IDCancer nameDesignSampleChangeRatioPubmed
ENSP00000385519Breast CancerNormal vs. CancertissueUp1.720346108
ENSP00000385519Brain CancerNormal vs. CancertissueUp4.618056677

Hyperphosphorylation site
CD14_HUMAN do not have hyperphosphorylation site.

Direct Interaction Pair
SourceTargetRelationshipResource
CD14_HUMANTLR4_HUMANotherKEGG
CD14_HUMANTAB1_HUMANotherKEGG

Function Annotation
KEGG Pathway
KEGG IDPathway
hsa05202Transcriptional misregulation in cancer
hsa04010MAPK signaling pathway
hsa04640Hematopoietic cell lineage
hsa05133Pertussis
hsa05130Pathogenic Escherichia coli infection
hsa05132Salmonella infection
hsa04620Toll-like receptor signaling pathway
hsa04145Phagosome
hsa05146Amoebiasis
hsa04810Regulation of actin cytoskeleton
hsa05152Tuberculosis
hsa05134Legionellosis
hsa04064NF-kappa B signaling pathway

Gene Ontology
GO IDGO_TermEvidenceOntology
GO:0001847opsonin receptor activityTASmolecular_function
GO:0031225anchored to membraneIEAcellular_component
GO:0045807positive regulation of endocytosisIEAbiological_process
GO:0006909phagocytosisTASbiological_process
GO:0006950response to stressIEAbiological_process
GO:0005576extracellular regionTAScellular_component
GO:0002237response to molecule of bacterial originIEAbiological_process
GO:0045087innate immune responseTASbiological_process
GO:0007249I-kappaB kinase/NF-kappaB cascadeTASbiological_process
GO:0009408response to heatIEAbiological_process
GO:0005615extracellular spaceIEAcellular_component
GO:0070891lipoteichoic acid bindingIDAmolecular_function
GO:0006954inflammatory responseIEAbiological_process
GO:0016019peptidoglycan receptor activityTASmolecular_function
GO:0010008endosome membraneTAScellular_component
GO:0001530lipopolysaccharide bindingIDAmolecular_function
GO:0009986cell surfaceIEAcellular_component
GO:0050715positive regulation of cytokine secretionIEAbiological_process
GO:0007166cell surface receptor signaling pathwayTASbiological_process
GO:0005515protein bindingIEAmolecular_function
GO:0006915apoptotic processTASbiological_process
GO:0032496response to lipopolysaccharideIEAbiological_process
GO:0032760positive regulation of tumor necrosis factor produIDAbiological_process
GO:0034142toll-like receptor 4 signaling pathwayTASbiological_process
GO:0045121membrane raftIEAcellular_component
GO:0071222cellular response to lipopolysaccharideIDAbiological_process
GO:0035666TRIF-dependent toll-like receptor signaling pathwaTASbiological_process
GO:0071223cellular response to lipoteichoic acidIDAbiological_process
GO:0008063Toll signaling pathwayTASbiological_process
GO:0005886plasma membraneIEAcellular_component
GO:0034138toll-like receptor 3 signaling pathwayTASbiological_process


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