| UniProt/SwissProt ID: | BCAP_HUMAN |
| Description: | phosphoinositide-3-kinase adaptor protein 1 [Source:HGNC Symbol;Acc:30034] |
| Location: | chr10 q24.1 |
| Node attribute: | substrate |
| Phosphorylation site |
| Position | PhosphoPeptide | Catalytic kinase | Source |
|---|---|---|---|
| S562 | VFAEKsQERPG | PhosphoSitePlus | |
| T658 | LRDSItRRQRE | PhosphoSitePlus | |
| Y133 | DEPETyVAAVK | PhosphoSitePlus | |
| Y513 | QEEDVyHTVDD | PhosphoSitePlus | |
| Y694 | VEFGVyESGPR | PhosphoSitePlus; HPRD; SysPTM | |
| Y163 | EKVVSySKQQN | PhosphoSitePlus | |
| S145 | AISEDsGCDSV | PhosphoSitePlus | |
| S642 | KKRSEsFRFQQ | PhosphoSitePlus; HPRD | |
| S718 | DWKTDsTSSTA | PhosphoSitePlus | |
| Y230 | KVENEyTISVK | PhosphoSitePlus | |
| Y553 | PDNEPyIFKVF | PhosphoSitePlus | |
| S575 | YVSSEsIRKGP | PhosphoSitePlus | |
| S656 | KRLRDsITRRQ | PhosphoSitePlus; HPRD | |
| Y594 | PQSSIyDPFAG | PhosphoSitePlus | |
| T151 | GCDSVtDTEPE | PhosphoSitePlus | |
| Y570 | RPGNFyVSSES | PhosphoSitePlus; HPRD | |
| Y419 | EADAVyESMAH | PhosphoSitePlus | |
| Dephosphorylation site |
| BCAP_HUMAN do not have dephosphorylation site. |
| Mutation site |
| Ensembl ID | Variation | Source | Cancer name | Pubmed |
|---|---|---|---|---|
| ENSP00000339826 | G495R | COSMIC | Skin Cancer | 21984974 | ENSP00000339826 | A136D | COSMIC | Head and Neck Cancer | 21798893 | ENSP00000360151 | T219M | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000339826 | T722K | COSMIC | Skin Cancer | 21984974 | ENSP00000339826 | T352S | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000339826 | T397M | BIOMART | Breast Cancer | 21930507, 21930502 | ENSP00000339826 | G313R | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000339826 | R478Q | COSMIC | Head and Neck Cancer | 21798897 | ENSP00000339826 | G618S | COSMIC | Ovarian Cancer | 21720365 |
| Differential expressed protein |
| BCAP_HUMAN is not differential expressed protein. |
| Hyperphosphorylation site |
| BCAP_HUMAN do not have hyperphosphorylation site. |
| Direct Interaction Pair |
| Source | Target | Relationship | Resource |
|---|---|---|---|
| KSYK_HUMAN | BCAP_HUMAN | kinase -> substrate | KEGG; NetPath |
| BTK_HUMAN | BCAP_HUMAN | kinase -> substrate | NetPath |
| Function Annotation |
| KEGG Pathway |
| KEGG ID | Pathway |
|---|---|
| hsa04662 | B cell receptor signaling pathway |
| Gene Ontology |
| GO ID | GO_Term | Evidence | Ontology |
|---|---|---|---|
| GO:0005737 | cytoplasm | IEA | cellular_component |
| GO:0005829 | cytosol | TAS | cellular_component |
| GO:0005886 | plasma membrane | IEA | cellular_component |
| GO:0005515 | protein binding | IEA | molecular_function |
| GO:0042802 | identical protein binding | IEA | molecular_function |
| GO:0005886 | plasma membrane | TAS | cellular_component |